Glanzmann's thrombasthenia: role of angioembolization and factor VII in recurrent bleeding from ulcerated duodenum

Introduction: Glanzmann's thrombasthenia [GT] is a rare, genetically inherited, functional disorder of platelets. The pathology is deficient or dysfunctional platelet glycoprotein IIb/IIIa [GP IIb/IIIa] complex resulting in bleeding diathesis

Case Report: Here in, we report the effectivity of angioembolization with factor VII in a patient with Glanzmann's thrombasthenia [GT], who presented with recurrent bleeding from duodenal ulcer

Conclusion: Angioembolization with added infusion of factor VII, can be considered an equally effective alternate to platelet transfusion in patients of GT, who present with recurrent bleeding

Epidemiology of hand injury in children

Objective: To study the types and presentation of hand injuries in children

Method and Materials: A prospective study was done at the emergency department of Jinnah Postgraduate Medical Centre from 24th October, 2014 to 30th December, 2014 [a duration of six weeks]. The data was collected on 50 out-patient children but we also followed the in-patient to find the outcome of their injuries. A self-designed questionnaire was administered and was filled by the parents of the participants. The questionnaire was explained in a one to one meeting by our volunteers. The volunteers were encouraging and friendly

Results: The most common reason of hand injury in our settings was due to road traffic accidents [34%]; followed by the second reason, a fall of an object on the hand. In most of the cases, 68% of the participants involved the right hand whereas in 32% of the participants, the left hand was involved. The most common bone to be fractured in children was the scaphoid with the 1st metacarpal bone

Conclusion: The goal of the study was to find out the various modes of presentation and types of the hand injuries in the accident and emergency department and to emphasize the regions commonly injured during a hand trauma. Better understanding of the type and manner of hand injuries will lead the physicians to emphasize on the areas more commonly injured and take suitable measures for their treatment accordingly. The rising number of hand injuries and knowledge about their pattern encourages the authorities to take suitable action and measures for its prevention and treatment which has been an area of neglect

Cross-sectional study: head injury in children of Karachi

A cross-sectional study was conducted to determine the prevalence, causes and outcome of head injury in children at Neurosurgery Department of Jinnah Postgraduate Medical Centre from 1st December, 2013 to 1st February, 2014. A total of 37 patients under the age of 12 years, presented with head injuries to the emergency department, were included in the study. A self-designed questionnaire was filled for these children after getting the oral consent from their parents. The questionnaire comprised a complete detail on the causes of head injury, clinical presentation on reaching the hospital, X-rays and Computed Tomography [CT] scans of the children and their reports. SPSS version 20 was utilized as an analytical tool. The mean age of patients was 6.93 years +/- 3.02. Out of these 37 patients, 54.1% were males and 45.9% were females. Road traffic accidents accounted for most of cases [48.6%] with marked peak observed in boys as compared to the girls. Majority had a good Glasgow Coma Scale [GCS] score [43.2%] whereas a depressed fracture was found to be the dominant feature [21.6%] on X-rays. Additionally, 29.7% of children had intracranial hemorrhage while 32.4% also acquired other injuries. In total 29.7% were offered surgical intervention with majority [83.8%] landing in neurosurgical ward. As head injury in childhood is an important issue, keeping in view the lack of research in this field we need to properly highlight the burden of such injuries in childhood so that all the concerned governing authorities should take every possible step in preventing as well as managing this devastating health concern

Isolated lesser Trochanteric fracture- a rare but possible clinical entity in adults

Isolated Trochanteric Fracture is a rare clinical entity in adults especially when it occurs due to trauma. Isolated traumatic fracture of lesser trochanter has been reported very rarely in the literature, as usually in adults, it is associated with malignancy which should be ruled out during the diagnosis