Metastatic prostate and renal cell carcinoma presenting as supra-clavicular lymphadenopathy: report of two cases

Most metastases of cancers to cervical lymph nodes including supra-clavicular chain are from the head and neck primary tumors. Cancers metastasizing to the supra-calvicular lymph nodes from non-head and neck origin are rare. This occurs most frequently with lung, breast and esophagus. For prostate cancer, the non-regional lymph nodal involvment is very rarely reported. Similarly renal cell carcinoma presents mostly in advanced stage disease with involvment of non-regional lymph nodes is much less common. We present two cases of prostate and renal cell carcinoma who presented with initial manifestation of supraclavicular lymphadenopathy

Metastatic prostate adenocarcinoma presenting with bilateral inguinal adenopathy

Metastatic prostate adenocarcinoma generally manifests either as painful bone metastases often in axial skeleton or as bulky iliac and para-aortic lymphadenopathy. The inguinal lymphadenopathy is very rare. Here-in we present an unusual case of metastatic prostate adenocarcinoma with bilateral inguinal adenopathy