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1.
Chinese Herbal Medicines ; (4): 291-291, 2021.
Article in Chinese | WPRIM | ID: wpr-953669

ABSTRACT

When this paper was first published the following ethical statement was omitted in error: The experiment was approved by Institutional Animal Ethical committee (IAEC) with an approval number (KSRCT/BT/IAEC/2017/20) and the experiment was conducted at Animal House facility, KS Rangasamy College of Technology, Tiruchengode, Namakkal District, Tamil Nadu, India. The authors would like to apologise for any inconvenience caused.

2.
Chinese Herbal Medicines ; (4): 152-156, 2018.
Article in Chinese | WPRIM | ID: wpr-842137

ABSTRACT

Objective: Mosquitoes are the major transmitting vectors of serious human diseases, causing millions of deaths every year with undesirable effects, including toxicity to non-target organisms. Some plants with insecticidal properties have been used in recent years for the control of a variety of pest insects and vectors. In the quest for alternative natural biological control agents against mosquito larvae lichens were selected. Method: Larvicidal activity was assessed with methanolic extracts of Parmotrema reticulatum, Parmotrema kamatti, Parmotrema tinctorum, Parmelia erumpens, Leptogium papilosum, and Roccella montagnei against Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus. The standard WHO protocols with minor modifications were adopted and the bioassay was evaluated at the concentrations of 100–500 µg/mL for each lichen. Since all the lichen extracts showed complete mortality against C. quinquefasciatus in 100 µg/mL, the concentrations were decreased to 100, 50, 25, 12.5, and 6.25 µg/mL for C. quinquefasciatus. Larval mortality was observed for 24 h after treatment. Results: All the lichen extracts exhibited activity against third instar larvae of A. aegypti and A. stephensi at 100 µg/mL, and 100% mortality was observed against the vector C. quinquefasciatus at 100 µg/mL. The highest larvicidal activity was found with L. papilosum against A. aegypti (LC50 = 81.127 µg/mL) and A. stephensi (LC50 = 89.10 µg/mL). Similarly, P. tinctorum and R. montagnei when tested against C. quinquefasciatus with minimum concentration <100 µg/mL exhibited significant activity with LC50 values of 5.32 and 6.97 µg/mL. Conclusion: The bioassay results revealed larvicidal potential of lichens especially against C. quinquefasciatus with high mortality even at lower concentration. Hence, lichens can be used as an ideal sustainable approach for the control of lymphatic filariasis caused by vector C. quinquefasciatus.

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