ABSTRACT
Objective: to determine the biochemical and ultra-sonographic noninvasive parameters in liver cirrhotic patients due to Hepatitis Band C virus. To validate the non-invasive parameters with the presence of esophageal varices using endoscopy as gold standard
Material and Methods: two hundred diagnosed patients were taken. Every patient underwent esophagogastroduodenoscopy [EGO] for the presence of esophageal varices. Ultrasonography was done to calculate the spleen diameter. Blood samples were taken to find the levels of blood ammonia and platelet count
Results: on the basis of Receiver operating curve [ROC] blood ammonia level had area under the curve [AUC] 1.000 [p<0.001] platelet count/spleen diameter ratio [AUC=0.008, p<0.001] platelet count [AUC 0.009, p<0.001] and spleen diameter had area under the curve 0.986 [p<0.001] The maximum area under the curve was observed with blood ammonia [100%] as compared to other parameters
Conclusion: it was concluded from the present study that blood ammonia level is the most reliable non-invasive parameter in predicting the presence of esophageal varices as compared to other non-invasive parameters