ABSTRACT
<p><b>OBJECTIVE</b>To study the aqueous constituents of Houttuynia cordata.</p><p><b>METHOD</b>Various columns including Diaion HP-20, Sephadex LH-20, ODS and silica gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis.</p><p><b>RESULT</b>Five compounds were isolated, and their structures were identified as chlorogenic methyl ester (1), (E)-4-Hydroxy-4-[3'-(beta-D-glucopyranosyloxy) butylidene]-3, 5, 5-trimethyl-2-cyclohexen-1-one (2), 2-(3, 4-dihydroxyphenyl) ethyl-beta-D-glucopyranoside (3), p-hydroxyphenethyl-beta-D-glucoside (4), 4-(beta-D-glucopyranosyloxy)-3-hydroxy-Benzoic acid (5).</p><p><b>CONCLUSION</b>All compounds were isolated from this plant for the first time.</p>
Subject(s)
Chlorogenic Acid , Chemistry , Chromatography, Gel , Cyclohexanones , Chemistry , Glucosides , Chemistry , Houttuynia , Chemistry , Magnetic Resonance Spectroscopy , Phenols , Chemistry , Plants, Medicinal , Chemistry , Spectrometry, Mass, Electrospray IonizationABSTRACT
<p><b>OBJECTIVE</b>To study the flavonoid constituents in fresh herb of Houttuynia cordata.</p><p><b>METHOD</b>Various column packing materials including Diaion HP - 20, Sephadex LH - 20, ODS and silica gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis.</p><p><b>RESULT</b>Five compounds were isolated, and their structures were identified as quercetin-3-O-beta-D-galactoside-7-O-beta-D-glucoside (1), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1 --> 6)-beta-D-glucopyranoside (2), quercitrin (3), hyperin (4), quercetin 3-O-alpha-L-rhamnopyranosyl-7-O-beta-D-glucopyranoside (5).</p><p><b>CONCLUSION</b>Compounds 1, 2 and 5 were separated from H. cordata for the first time.</p>