Type of tooth movement during en masse retraction of the maxillary anterior teeth using labial versus lingual biocreative therapy in adults: A randomized clinical trial / 대한치과교정학회지

OBJECTIVE@#The objective of this two-arm parallel trial was to compare the type of tooth movement during en masse retraction of the maxillary anterior teeth using labial versus lingual biocreative therapy.@*METHODS@#Twenty-eight subjects were randomized in a 1 : 1 ratio to either the labial or lingual group. En masse anterior retraction was performed using labial biocreative therapy in group A and lingual biocreative therapy in group B. Cone beam computed tomography scans were taken before and after retraction and the primary outcome was the type of tooth movement during anterior retraction. Data were analyzed using paired t-tests for comparisons within each group and independent-sample t-test for comparison of the mean treatment changes between the two groups.@*RESULTS@#Significant differences were found between the two groups in relation to the type of tooth movement (labiolingual inclination of the central incisor; mean difference, 5.85 ± 1.85°). The canine showed significant distal tipping in the lingual group (mean difference, 6.98 ± 1.25°). The canine was significantly more intruded in the lingual group (mean difference, 1.67 ± 0.49 mm). Good anchorage control and significant soft tissue changes occurred in both groups. No serious adverse effects were detected.@*CONCLUSIONS@#With a 10-mm retraction hook, the labial biocreative technique with the reverse curve overlay provided anterior retraction with good torque control, while in the lingual group, anterior retraction occurred with controlled tipping movement with significant distal tipping and intrusion of the canine (trial registration: The trial was registered at ClinicalTrials.gov [NCT03239275]).

Prognostic value of C-reactive protein in acute coronary syndrome

It is well recognized that inflammation plays a key role in acute coronary syndromes [ACS]. Researchers have turned to biochemical markers of inflammation as possible noninvasive predictors of high risk. High-sensitivity measurement of C-reactive protein [hs-CRP] is one of the most extensively studied biochemical markers. Recent studies had suggested a significant association between its level and the risk of future cardiovascular events in patients with ACS. In this study, serial measurements of hs-CRP were performed in patients with ACS admitted in Sohag university hospital to find out its prognostic value and evaluate its possible use for risk stratification. This study included 150 patients who were admitted to coronary care unit in Sohag University hospital with the diagnosis of ACS [unstable angina-Acute Myocardial infarction]. Clinical and laboratory assessment as well as hs-CRP measurements were performed on admission and at monthly interval for 6 months. Angiographic analyses were performed for 68 patients. Development of major adverse cardiac events [MACE] or cardiac deaths during the follow-up period were recorded. The study included 50 patients with unstable angina, 100 patients with myocardial infarction. In the 1st group; MACE occurred in 10 patients [20%] and mortality in 3 [6%] patients. In the 2nd group; MACE occurred in 16 patients [16%] and mortality in 8 patients [8%]. The median level of hs-CRP was high in all groups on admission [3.5 [1.5-6.9]]. A significantly higher on-admission levels of hs-CRP were observed in patient with MACE during the follow-up period as compared to those with no MACE with a P value=0.021 in both groups. The estimated hazard ratio was increased more than 2 folds in patients with higher hs-CRP in both groups. MACE were significantly associated with the disease extent and extent score [p=0.4 and 0.5 respectively] in both groups, but the later 2 factors were not associated with increase in hazard ratio [1.1 and 1.00 respectively]. Mortality was associated with significantly higher median levels of hs-CRP in both groups. Monthly measurements of hs-CRP shows significantly higher median levels in patients with MACE at the 1st and 2nd month in patients with UA [p=0.034 and 0.049 respectively] and at the 1st month only[p=0.026] in patients with MI. Measurement of hs-CRP in patients with ACS is a simple, reproducible and adds to the predictive value of traditional risk factors. Its measurement is recommended in routine clinical practice for risk stratification in acute coronary syndromes

Experimental murine toxocara canis histopathological study of chronic renal infection, transplacental transmission and ultrastructural study of egg shell

Histopathological examination of kidney of Swiss albino mice, 21/2 months after infection with Toxocara canis eggs revealed various pictures of pathological affection. There was diffuse mesangioproliferative glomerulonephritis with mesangial expansion of most of glomeruli. Some glomeruli showed severe hyalinosis with marked adhesions to the bowman's capsule. The lumina of glomerular capillaries were markedly obliterated. There was also cystic dilation of tubules with proteinaceous casts. The interstitial tissue showed mild inflammatory edema. Chronic inflammatory cellular infiltration to form granulomatous inflammation was noticed. Transplacental transmission of Toxocara larvae was assessed in embryo of pregnant female Swiss albino mice which were infected with Toxocara eggs in the 1st week of pregnancy. The larvae were detected in the liver of embryo. Ultrastructural study of the egg shell revealed its formation of four layers, a thin uterine membrane with occasional small bulges, vitelline layer, thick homogenous layer, and fibrous lamellar and lipid layer

Introduction to seismocardiography

Seismocardiography is a new noninvasive technique for recording cardiac vibrations. It is a form of displacement cardiology, a field that includes apexocardiography, kinetocardiography, ballistocardiography and cardiokymography

Effect of repeated doses of praziquantel on the liver of premature albino mice

Bilharziasis constitutes a national health problem in Egypt. Millions of individuals were infested with bilharziasis. They form continuous source of infection and spread of the disease allover the country. Praziquantel, the antischistosomal drug was given successfully in a single oral dose. Some workers divided the single dose twice or trice. Others repeated the dose using different regimens with encouraging results. In the present work, therapeutic dose of praziquantel was administered for 5 days to postnatal Swiss albino mice aiming to detect the teratogenic, toxic or pathologic effects on their livers. It was observed that praziquantel induced variable degenerative changes in the liver in the form of focal areas of cell necrosis, fatty degeneration with mild inflammatory cell infiltration in the first and the second days after stop of the drug. These degenerative changes were massive 7 days later

Parasitic [helminthic] infection among Babil school children at Menofia governorate

This study was carried out at Babil Primary Schools. The target sample was composed of 800 males and 600 females. Their ages ranged from 6-12 years. The results showed that 25.5% of total sample were suffering from parasitism. The most prevalent parasites were Schistosoma hematobium [10.1%], followed by Ascaris lumbricoides [6.9%]. Schistosoma mansoni [4.5%] Enterobius vermicularis [3.3%], the last parasite detected was Hymenolepis nana [2.4%]. It was observed that there is a significant difference between infection rate among high and low social classes also between infected and non infected groups regarding to personal habits and environmental conditions. Evaluation of the nutritional status of the children cleared that there is observable growth retardation among the infected group. Socio-economic development, environmental sanitation, health education, active participation of school authorities for early diagnosis and treatment of parasitism are highly recommended