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1.
Rev. Inst. Med. Trop. Säo Paulo ; 42(6): 313-20, Nov.-Dec. 2000. tab
Article in English | LILACS | ID: lil-274888

ABSTRACT

PURPOSE: To evaluate the frequency and the consequences of the co-infection of hepatitis B and C viruses in patients with hepatosplenic schistosomiasis (HSS). METHODS: B and C serologic markers, exposure to risk factors, biochemical assays, upper gastrointestinal endoscopies, and abdominal ultrasonograms were evaluated in 101 patients with HSS from 1994 to 1997. Whenever possible, PCR was tested and histopathological studies were reviewed. RESULTS: At least one HBV virus marker was found in 15.8 percent, and anti-HCV was detected in 12.9 percent of the subjects. The seropositive subjects tended to be older than the seronegative ones. A history of blood transfusion was significantly related to the presence of anti-HCV. Three (18.75 percent) out of 16 subjects exposed to B virus were HBsAg positive. Eleven (84.6 percent) out of thirteen patients who were anti-HCV positive demonstrated viral activity. Patients with ongoing viral infection presented a higher average level of liver aminotransferases, a higher frequency of cell decompensation and a higher rate of chronic hepatitis. Portal hypertension parameters were not influenced by viral exposure. CONCLUSIONS: The rate of hepatitis B and C viruses serologic markers observed in the patients with HSS was higher than the control group. The co-infection was responsible for a higher frequency of cell decompensation


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Hepatitis B Antibodies/blood , Hepatitis C Antibodies/blood , Schistosomiasis mansoni/immunology , Splenic Diseases/immunology , Biomarkers/blood , Case-Control Studies , Chi-Square Distribution , Hepatitis B/complications , Hepatitis C/complications , Risk Factors , Schistosomiasis mansoni/complications , Splenic Diseases/complications , Splenic Diseases/parasitology , Statistics, Nonparametric
2.
Rev. nutr ; 12(3): 233-239, set.-dez. 1999. tab, graf
Article in Portuguese | LILACS | ID: lil-302191

ABSTRACT

Com o objetivo de avaliar a presença de desnutrição proteíco-energética em pacientes hospitalizados, realizou-se um estudo com 57 doentes admitidos consecutivamente para internação na enfermaria de Gastroenterologia Clínica no período de dezembro de 1996 a junho de 1997. A maioria dos pacientes estudados era de sexo feminino (63,2 por cento) e as hepatopatias caracterizavam-se como doença predominante (77,2 por cento), seguidas de enteropatias (10,5 por cento), pancreatopatias (5,3 por cento), gastropatias (3,5 por cento) e outras (3,5 por cento). o estado nutricional foi avaliado objetivamente por meio de medidas antropemétricas e bioquímicas e, subjetivamente, por meio de um questionário sistematizado por Detsky. Ambos os métodos foram realizados pelo mesmo observador. Verificou-se que 68,5 por cento dos pacientes apresentavam estado nutricional aceitável, 21,0 por cento desnutrição moderada e 10,5 por cento desnutrição grave. Em vista dos resultados, pode-se concluir que é frequente a ocorrência de desnutrição ou risco nutricional em doentes hospitalizados com doenças gastrintestinais, sendo que a detecção prévia da desnutrição proteíco-energética é de grande importância para que uma terapia nutricional adequada seja oferecida ao paciente


Subject(s)
Humans , Nutritional Status , Inpatients , Nutrition Assessment , Protein-Energy Malnutrition
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