Clinical Observation of Incontinentia Pigmenti / 대한피부과학회지

The clinical observation was done on 9 patients of incontinentia pigmenti(I,P.) who were seen at the Department of Dermatology, Chonnam University Hospital from January, 1970 through December, 1982. The incidence of I.P. patients among the population of Chonnam province was higher than 1/142,000 whereas the frequency of I.P. among the outpatients was 0.016% The sex of I.P. patients was all female and there was no cases showing faiailial occurrence. The onset of the cases were within 4 months after birth, 44%, being at birth and 89% being within 2 weeks after birth. The durations of first, second and third stages of I.P. patients were respectively 14 days, 15 days to 2 months, and 2 months to 10 months. The trunk and extremities were involved in 4 cases, and the extremities only were involved in 4 cases while the trunk only was involved in J case. The blood eosinophilia was observed in 2 cases among 7 cases, with their results being 18%, and 11% respectively. The biopsy examinations done in 7 cases at the time of their first visits revealed that 3 cases, 2 cases and 1 case respectively conformed to first, second and third stages with 1 case having first and second stages simu 1taneously. There was no I.P. patient showing the associated congenital abnorma- lity.

The Frequency and Clinical Observation of Ota's Nevus / 대한피부과학회지

The clinical observation was done on 126 patients of Ota's nevus, 113 of whom were seen at Department of Dermatology, Chonnam National University Hospital from January 1973 through July 1983, and 13 of whom were found among 45, 87l male and female students of high school in Kwangju City, Korea. The results obtained were as follows: 1. The incidence of male and female students of Ota's nevus were respectively 0. 013% and 0.043%, with the incidence,as a whole being 0.03%, whereas the frequency of Ota's nevus among the outpatients was 0. 24% with the ratio of male to female being 1: 2. 67. 2. There was only one family of familial occurrence, in which 2 sisters were involved among 5 siblings. 3. Thirty three percent of Ota's nevus showed the onset at birth. 4. According to Tanino's classification, our patients showed that Type II was 41.7% and then Type Ia, III, Ib, and IV being respectively 33. 3%, 16. 7, 4.2, and 4. 2%. 5. Seleral involvement was 54.2%, especially in type III and Type II. 6. The color was increased in 54%, especially Type II by internal and external factors such as fatigue, warm temperature, menstruation and cold temperature. 7. The color intensification was prominent at the age of 10 to 14.

Necrobiosis Lipoidica: Report of a Case / 대한피부과학회지

Necrobiosis Lipoidica is a skin disorder of unknown cause, which shows characteristic clinical and histological findings. With histochemical studies, we report of a case which oecurred on the both pretibial surfaces in a 5]-year-old female. Having had treatment with aspirin and dipyridarnole for 9 months. The results were successful.

A Case of Epithelioma Cuniculatum / 대한피부과학회지

Epithelioma cuniculatum or plantar verrucous carcinoma shows a great tendency toward deep penetrating growth, resulting in numerous crypts filled with horny material and pus. We herein described a 44 year-old female who showed a warty, relatively round, brown to yellow colored protruding mass with many crypts filled with pus-like exudates, measuring 2.3 X 2.5 X 1.5 cm in size, and of 5 years duration. The biopsy specimen taken from the tumor mass revealed a deeply penetrating, well-differentiated squarnous cell carcinoma without nuclear anaplasia and individual cell keratinization.

Leiomyosarcoma of the Skin: Report of A Case / 대한피부과학회지

Leiomyosarcoma arising in the skin is rare tumor, and diagnosis usually is made microscopically. After local excision, these lesions recur in large proportion of pat ients. The authors herein report a 53-year-old male with leiomyosarcoma appeared in the skin of the right forearm and presenting as a dark reddish colored, 5*6cm in diameter, superficial ulcerated single firm nodule with intermittent pain. Histopathological examination showed poorly circumscribed tumor consisting of interlacing bundles of spindle shaped smooth muscle cells in the middle and lower parts of the dermis. The nuclei were hyperchromatic, large, vacuolated, and irregular in shape. Electron microscopic findings revealed cytoplasmic organelles such as rough endoplasmic reticulum and mitochondria of malignant smooth muscle cells in the paranuclear area, Characteristic subsarcoelmmal caveolae and dense plaque were noted and myofilaments were distributed in the peripheral cytoplasm. The tumor did not recur in 10 months' follow-up.