ABSTRACT
OBJECTIVES: We investigated the significance of interoceptive fear in assessment of panic disorder (PD) patients. METHODS: 102 patients affected by PDs with (n=68) or without (n=34) agoraphobia according to DSM-IV criteria completed self-report questionnaires, such as Albany Panic and Phobia Questionnaire (APPQ), The Expanded Anxiety Sensitivity Index (ASI-R), Agoraphobic Cognitions Questionnaire (ACQ), Body Sensation Questionnaire (BSQ), Beck Anxiety Inventory (BAI), and Panic Disorder Severity Scale (PDSS). Pearson correlation analysis, stepwise regression analysis, paired t-test and independent t-test were used. RESULTS: All variables except BSQ were significantly correlated with panic severity. In stepwise regression analysis, interoceptive fear and catastrophic cognition were the most significant predicting variables for panic severity. After 3-months medication, all variables significantly diminished, but interoceptive fear and catastrophic cognition of panic patients were still significantly higher than normal control. CONCLUSION: Interoceptive fear is the fear of automatic sensations that are similar to those of a panic attack and is the most significant variable in predicting panic severity. After 3-months medication, interoceptive fear significantly decreased, but still was higher than the control group.