ABSTRACT
Objective: To study the effect of the stress distribution with three dimensional(3-D) finite element analysis technique between zirconia all-ceramic crown of maxillary central incisors and agglomerant with different thickness. Methods: A 3-D finite element model of all-ceramic crown (core layer and the veneer layer), agglomerant, tooth, tooth root and alveolar bone was established from CBCT data. The agglomerant thickness was designe as 50, 100 and 150 μm respectively. After a load simulating occlusion was imposed on to the model the stress distribution of agglomerant layer, the equivalent of veneer layer and the maximum principal stress were analysed. Results: With the increase of agglomerant thickness and the change of occlusion, the maximum principal stress of all ceramic crowns gradually increased, the equivalent stress increased first and then decreased, the equivalent stress and the maximum principal stress of agglomerant layer showed a downward trend. Conclusion: The use of agglomerant layer with the thickness of 50 μm is feasible for the bond of all ceramic crowns and may reduce the risk of veneer chipping.
ABSTRACT
Objective To investigate the inhibitory effects of arsenic trioxide on salivary duct carcinoma cell colony and to explore a new approach to treat salivary duct carcinoma .Methods Human salivary duct carci-noma cancer cells were established .The effects of different concentrations (0.5、1、2、4μmol/L)and time(48,96 H) of arsenic trioxid on salivary duct carcinoma cell colony and the changes of the cell colony were observed with MTT assay and microscopic cell analysis .Results Human salivary duct carcinoma were significantly inhibited by Different concentrations of arsenic trioxide at different times points , and the relationship between the doses and time points are dependent ,cell atypia disappearing apoptosis appears apoptotic bodies .Conclusion Arsenic tri-oxide can significantly inhibit proliferation ,induce differentiation and promote apoptosis in the salivary duct carci-noma cells .
ABSTRACT
Objective:To observe the effects of Xiaozhiling on the serum vascular endothelial growth factor(VEGF) level of the patients with hemangioma.Methods:10 healthy subjects (control group) and 10 hemangioma patients (treatment group) were included.The serum VEGF level were evaluated by ELISA in both groups.The treatment group was injected with Xiaozhiling once.VEGF level of the treatment group were measured before, one week after and one month(only 8 patients) after Xiaozhiling injection.Results:The serum VEGF concentrations (pg/ml) of the healty subjects, hemangioma patients without treatment, the patients 1 week after injection of Xiaozhiling and those 1 month after injection were 97.3?15.1,799.3?84.1,828.1?68.8 and 105.6?13.5 respectively. 1 week after injection tumor volume decreased by more than 25% in all the 10 patients.Conclusions:In situ injection of Xiaozhi ling may be a method for the treatment of hemangioma.