Clinical and biochemical study of 114 cases of cholelithiasis

During a period of 16 months 114 patients with cholelithiasis were studied. The diagnosis was confirmed by cholecystogram in 41 cases, by surgery in 28 and both surgery and the x-ray in 45 cases. There were 100 females and 14 males and their average age was 43.2 years. The average number of pregnancies in females was 6.5. Clinically the jaundice was observed in 9 percent and the gall bladder was palpable in 47 percent of cases. Cholelithiasis appeared to be related to increased parity but not to the body weight

Rupture of the uterus in full-term pregnancy

Of 48,519 deliveries conducted at Jinnah Postgraduate Medical Centre [JPMC] over 7 years [January, 1986 to December, 1992], 257 were of ruptured uterus, giving a rate of one in 189 deliveries. Main cause of rupture was obstructed labour. Maternal mortality was 3.9% and foetal mortality 88% in cases admitted with uterine rupture and 17.6% in rupture occurring within the hospital

Dietary and serum calcium in pregnant women

Dietary and serum calcium were estimated in 200 normal pregnant women between 37-41 weeks of gestation and in cord blood of their new born. Calcium intake per person per day was low, 11.8mmol/L, as compared with the daily recommended allowance of 30 mmol/L Mean maternal serum calcium level was also low [1.9 mmol/L] and only 20% of mothers had serum calcium within normal range. Mean calcium value in cord blood was at lower limit of normal range, being 2.3 mmol/L; 38.5% of cord samples [77] were below the normal range

Maternal factors affecting birthweight of uncomplicated pregnancy

Two hundred full-term pregnant mothers with no complication of pregnancy and no associated disease selected from Jinnah Postgraduate Medical Centre were studied for their nutritional status and other characteristics. The effect of these factors on birthweight of their new-born was determined. Total calorie intake per capita per day was low being 1913. The mean birthweight was 2.9kg, 26% weighed 2.5kg or less. No significant sex difference was observed in the birthweight. Variables having a significant positive influence on birthweight were maternal age at first delivery, upto 25 years, beyond which correlation was not significant; maternal weight and maternal total calorie intake [irrespective of source] upto an intake of 2500 calorie per day, beyond which correlation was not significant. Combined effect of these three maternal factors on birthweight was highly significant. Coefficient of correlation, R being 0.81

Serum calcium, urea and uric acid levels in pre-eclampsia

Serum calcium, urea and uric acid levels were determined in 100 normal pregnant women and 50 patients with pre-eclampsia. Serum calcium levels were significantly lower and urea and uric acid levels higher in pre-eclampsia. Low levels of calcium were found as early as 28 weeks and can therefore be used for early diagnosis of pre-eclampsia

Maternal morbidity in the department of obstetric and gynecology, Jinnah postgraduate medical centre Karachi

Maternal morbidity was observed in 377 obstetric cases at Jinnah Postgraduate Medical Centre [JPMC] during a period of one year. Morbidity rate was 4.4% of total deliveries. Three hundred and twenty-four [86%] mothers had no proper antenatal supervision. Infection was more common after abdominal delivery and injury to genital tract after vaginal delivery. The most serious injury was rupture of gravid uterus. Thirty-seven cases of ruptured uterus were admitted in one year and 5 cases occurred within the hospital [1 in 1225 deliveries]

Maternal characteristics and birthweight

One thousand and twenty-five full term pregnant mothers and their newborn were studied. Overall mean Birthweight was 2.9 kg. Twenty-six percent of newborn weighed<2.5kg. Maternal age at first delivery, maternal total caloric in take and maternal weight had a significant positive influence on Birthweight