ABSTRACT
Objective: The aim of this work was to study the effect of parathyroidectomy on patients with tertiary hyperparathyroidism, and to determine whether patients with tertiary hyperparathyroidism due to single- or two- gland disease undergoing limited resection have similar outcomes compared with patients with hyperplasia undergoing subtotal parathyroidectomy
Patients and Methods: A total number of 15 patients with manifestations of tertiary hyperparathyroidism underwent parathyroidectomy, where patients with adenoma[s] of parathyroid gland underwent excision of only the adenoma[s], and patients with hyperplasia of parathyroid gland underwent subtotal parathyroidectomy
Results: There were significant changes in both clinical and laboratory values between pre- and post operative measures in both types of patients [adenoma and hyperplasia]. This was proved by the significant decrease in serum calcium, serum alkaline phosphatase and parathyroid hormone as well as the great clinical improvement in the preoperative manifestations
Conclusion: From this study we can conclude that the optimal treatment of tertiary hyperparathyroidism is surgical excision of adenoma[s] in patients with parathyroid adenoma[s] or subtotal parathyroidectomy in patients with hyperplasia of parathyroid gland