ABSTRACT
This study was made to evaluate the value of the IHA test for streptococcal antibodies in children with acute rheumatic fever in comparison with the conventional ASO titer. The upper limit titers of ASO and IHA in control group were 170 and 640 respectively. All sera from 37 patients with rheumatic fever had IHA titers over 640. In contrast, the level of ASO titer above upper normal limits was found in only 62% of these cases. This report present data which favours the use of IHA test. Its sensitivity is very similar to that of the commercial Anti Streptozyme test. In addition, the test is simple and could be performed economically. More studies are needed to evaluate the test further. If the results proved as favourable as this report a negative test would be of a considerable value in excluding the diagnosis of acute, rheumatic fever especially in questionable cases.
Subject(s)
Acute Disease , Adolescent , Antibodies, Bacterial/analysis , Antistreptolysin/analysis , Child , Female , Hemagglutination Tests , Humans , Male , Rheumatic Fever/diagnosis , Streptococcus pyogenes/immunologyABSTRACT
Two cases of nephrotic syndrome with coagulopathy were presented. The first case was due to acquired factor IX deficiency. The second case was due to unexplanable prolonged thrombin time.
Subject(s)
Biopsy , Blood Coagulation Disorders/blood , Child , Hematuria/blood , Hemophilia B/blood , Humans , Kidney/pathology , Male , Nephrotic Syndrome/blood , Partial Thromboplastin Time , Prothrombin Time , Thrombin TimeABSTRACT
Determination of diphtheria and tetanus antitoxin levels by an indirect haemagglutination method were conducted in 101 nonimmunized schoolchildren, 155 pediatric patients and 102 blood donors. Diphtheria and tetanus antitoxin levels were found mostly adequate among immunized children. Diphtheria antitoxin levels were found adequate in 68.3% of the non-immunized schoolchildren. Tetanus antitoxin levels were found inadequate for protection in the non-immunized children and adults. Immunization of children and adults with diphtheria and tetanus toxoid are highly recommended.
Subject(s)
Adult , Age Factors , Child , Diphtheria Antitoxin/analysis , Humans , Immunization , Tetanus Antitoxin/analysis , ThailandSubject(s)
Child , Female , Furosemide/administration & dosage , Humans , Acute Kidney Injury/drug therapy , MaleABSTRACT
This prospective study showed that thalassaemic patients, though susceptible to streptococcal infection, as evident from their elevated A.S.O. titres, are not, as has been suggested, more likely to develop acute glomerulonephritis than the rest of the population. The incidence of thalassaemic trait found among typical cases of acute glomerulonephritis does not exceed that of the general Thai population. There were 5 out of 56 cases of thalassaemic patients having transient microscopic haematuria.
Subject(s)
Acute Disease , Adolescent , Antistreptolysin/analysis , Child , Child, Preschool , Glomerulonephritis/complications , Humans , Proteinuria/complications , Streptococcal Infections/complications , Thalassemia/complicationsABSTRACT
The examination of the hair roots were performed by a modified technique as described by Bradfield. The mean hair bulb diameter in children with overt nephrotic syndrome was statistically smaller than the controls. The distributions of hair root morphology amongst them were also statistically different from those of the control group. The hair roots of the children with remission or with questionable relapse were not different from the control group. The application of hair root examination, therefore may be useful in the differentiation of various stages of the nephrotic syndrome.