Obstetrical acute renal failure; analysis and outcome of patients in tertiary care hospital

Background and Objective: Acute renal failure is one of serious complication in pregnancy, in first trimester is usually related to unregulated and septic miscarriage while in third trimester it is due to obstetric complications. This prospective case serious descriptive study was conducted to determine the frequency, etiology and outcome of patients suffering from acute renal failure

Settings: Department of Gynecology and Obstetric at Liaquat University Hospital Hyderabad

Duration: One year [from 1st June 2011 to 31st May 2012]

Patients and Methods: Patients admitted in labor room during antepartum, intrapartum or post partum period were scrutinized by history, clinical examination, and investigations. Those with urine output less than 50cc in 24 hours were defined as case of ARF. Predesigned proforma filled to analyze etiology and outcome of patients with acute renal failure

Results: Out of 3220 patients admitted, 35 patients presented with acute renal failure giving incidence of 1.080%. APH[28.57%], PPH[25.7%], P.sepsis [14.28%] and Hypertensive disorder[5.14%] were leading cause of ARF. 60% patients recovered from injury and mortality in these patients were 11.4%

Conclusions: Poor health care facilities and lack of quality antenatal healthcare clinics were the major identified causes

Uterine rupture; its maternal consequenses

To evaluate frequency, maternal morbidity and mortality in patients with uterine rupture at Gynae Unit -II of civil Hospital Hyderabad. Prospective descriptive study. Department of Obstetrics and Gynecology, unit-ll Liaquat University Hospital Hyderabad Sindh Pakistan; from 1st October 2010 to 31st March 2011. All the patients diagnosed as case of uterine rupture was taken as study subject. Data was collected in a pre-designed porforma. Variable analyzed were frequency, demographic characters, maternal morbidity and mortality. During the study, 34 patients out of 1400 deliveries presented with uterine rupture resulting in a frequency of 2.42%or 1:41 deliveries. 64.7%[22] patients were between 26 to 35 years age and 67.64%[23] were multipara.26.47%[9] presented with extension of tears, 17.6%[6] with shock,20.5%[7] with septicemia and 20.5%[7] with wound infection. Uterine rupture is yet a common obstetrical emergency in our area. The significant morbidity and mortality deserves our special attention by a collaborative approach. Regular ante natal checkups, careful selection of patients for vaginal delivery, vigilantly monitoring during labor with smooth switch over to operative delivery can reduce this drastic obstetrical complication

Frequency and pattern of herpes zoster at Liaquat University Hospital Hyderabad [six months hospital based descriptive study]

Objective: to determine the frequency and pattern of herpes zoster at Liaquat University Hospital, Hyderabad

Patiehts and methods: this hospital based descriptive study of six months was carried out at Liaquat University Hospital, Hyderabad [Sindh] Pakistan; from March 2008 to August 2008. All patients who were above 12 years of age, attended the dermatology OPD and were diagnosed as cases of Herpes Zoster were evaluated and enrolled in the study. The diagnosis was established by history and relevant clinical examination. The data were collected on pre-designed proforma, saved and analyzed in SPSS version 10.00. The frequency and percentage of herpes zoster was calculated by detecting the number of positive cases while the pattern was assessed through prodromal, presenting symptoms, dermatome involved and observation of certain complications

Result: one hundred and ten patients were diagnosed as herpes zoster infection with mean age 38.9 +/- 10.79 years. Majority [80%] of the patients was presented in the Department of Dermatology and 76% were males. The most common prodromal symptom was paresthesia in 40 patients, itching in 35 patients, fever and headache in 20 patients, tingling in 15 patients, watering from eyes in 12 patients and burning in 10 patients. The dermatomes involved were thoracic in 78 patients, trigeminal nerve in 12 patients, lumber in 10 patients, cervical in 08 patients, and sacral in 02 patients. The complications seen were secondary infection in 42 [38%] patients, scarring in 18 [16%] patients, and post-herpetic neuralgia [PHN] in 15 [14%] patients

Conclusion: herpes zoster is a common viral infection and can be prevented when necessary by patient isolation and passive prophylaxis with varicella-zoster immune globulin. An experimental live vaccine also prevents varicella, but problems regarding its virulence for immunosuppressed patients and the durability of the protective response are still being addressed

Serum zinc level in patients with liver cirrhosis

To determine the serum zinc level in patients with liver cirrhosis. This descriptive cross sectional study was conducted at Liaquat University Hospital Hyderabad Sindh, Pakistan. All patients above 12 years of age, of either gender and known [diagnosed] cases of liver cirrhosis were further evaluated for their serum zinc level. The data was analyzed in statistical software [SPSS] and the p value <0.05 was considered as statistically significant. One hundred twenty seven cirrhotic patients with means age 42.7559 +/- 15.8894 were evaluated and assessed. The serum zinc was low in 69% patients. According to Child-Pugh classification 72% zinc deficient cirrhotic subjects were in class C, 16% in class B and 12% in class A. 94% subjects had hepatitis C virus infection, 4% had hepatitis B virus infection and 2% had history of alcoholism. The serum zinc level was low in patients with liver cirrhosis