ABSTRACT
The physiological changes in thyroid gland during pregnancy have been suggested as one of the pathophysiologic causes of preeclampsia. The aim of this study was comparison of serum levels of Tri-iodothyronine [T3], Thyroxine [T4], and Thyroid-Stimulating Hormone [TSH] in preeclampsia and normal pregnancy. In this case-control study, 40 normal pregnant women and 40 cases of preeclamsia in third trimester of pregnancy were evaluated. They were compared for serum levels of Free T3 [FT3], Free T4 [FT4] and TSH. The data was analyzed by SPSS software with the use of t-student, Chi-square, Independent sample T-test and Bivariate correlation test. P = 0.05 was considered statistically significant. The mean age was not statistically different between two groups [p=0.297]. No significant difference was observed in terms of parity between two groups [=0.206]. Normal pregnant women were not significantly different from preeclamsia cases in the view of FT3 level [1.38 pg/ml vs. 1.41 pg/ml, =0.8.03], FT4 level [0.95 pg/ml vs. 0.96 pg/ml, =0.834] and TSH level [3.51 micro IU/ml, =0.386]. The findings of the present study do not support the hyothesis that changes in FT3, FT4 and TSH levels could be possible etiology of preeclamsia
Subject(s)
Humans , Female , Pre-Eclampsia/blood , Pre-Eclampsia/physiopathology , Triiodothyronine/blood , Thyroxine/blood , Thyroid Function Tests , Pregnancy Trimester, Third , Case-Control Studies , Pregnancy/bloodABSTRACT
Approximately 30% of patients with renal cell carcinoma present with metastatic disease at the time of diagnosis. Metastasis of renal cell carcinoma to the vagina is rare. A 61 year old female presented with a vaginal lesion which was excised and diagnosed as metastatic clear cell carcinoma. A workup further is done Radiological studies revealed a left renal mass; A subsequent nephrectomy confirmed renal cell carcinoma. Renal cell carcinoma must be in the differential diagnosis of a vaginal clear cell neoplasm in a postmenopausal woman