Human clinical and histological responses of tricalcuim phosphate sodium fusidate alloplast mixture in fifteen intrabony defects

Fifteen intrabony defects in ten volunteer subjects were monitored clinically and histologically after filling with tricalcium phosphate sodium fusidate mixture. The purpose of the study was to test the particle mixture ability in regenerating osseous defects and to assess the bioacceptability of the mixture in human bone and soft tissues. Clinical results showed a reduction of average probing depth of 3.8 mm and an average gain in attachment level of 1.74 mm in comparison to pre-surgical status. Re-entery data showed that the graft mixture resulted in 60 percent overall defect fill. Histological responses of the implant sites showed that the mixture was well tolerated by the tissues and the material was in a process of degradation. Presented data indicate that the mixture could be helpful in facilitating regeneration of periodontal intrabony defects

Immunohistochemical characterization of bladder carcinoma associated with schistosomiasis

Fifteen cases of bladder carcinoma associated with schistosomiasis were studied for the expression of blood group antigens A and B, T-antigen and carcinoembryonic antigen [CEA] in an effort to correlate these data with the histologic grade of the tumour. The immunoperoxidase technique was used. It was found that blood group antigens are maintained better in low grade tumours. On the other hand, T-antigen positivity was correlated with invasive and high grade tumours. As regards the carcinoembryonic antigen, better expression was observed in high grade tumours. This study illustrates the value of combining three predictive tumour markers to more accurately assess the prognosis of patients with bladder cancer associated with schistosomiasis