ABSTRACT
Objective: 1. To identify the fluorescent signal pattens on WBC histograms in flowcytometry based, five parts differential haematology analyzers, in smear positive cases. 2. To make a diagnostic algorithm based on haematological parameters and WBC scattergrams in suspicious cases of P vivax malaria
Methods: seventy smear positive Plasmodium vivax haematological indices on automated 5 part differential hematology analyzers [XE2100 and XE5000] were checked for seminal use as potential diagnostic markers
Results: seventy smear positive Plasmodium vivax malaria cases were selected. Haematological indices revealed that 83.4% had thrombocytopenia. Pseudoeosinophilia was seen in 76.4% cases with 51/68 showing more than 5% gap. Considerable anaemia [Hb <10 g/dl] was exhibited by 32.8% of the patients. Leukopenia was seen only in 11 cases. Monocytosis was seen in 30 patients
Conclusion: CBC run on automated analyzers gives information in the form of an integrated pattern of results. When thrombocytopenia along with raised MPV and POW, anemia, leukopenia, monocytosis, eosinophilia [Pseudoeosinophilia in actual], abnormalities of WBC scatter-grams, monocytosis and altered ROW are read in collaboration lead to strong suspicion of P vivax malaria infestation
ABSTRACT
Objective: to isolate/identify device associated bacteria with their antibiotic sensitivity/resistance patterns in 2015 and to compare them with such 2010 results. Further the impact of MSDS on device associated infections
Methods: this cross-sectional study was carried out by the Microbiology Laboratory on devices or device-associated samples from intensive care units of Services Hospital Lahore in 2015. Bacteria were identified and their antibiotic sensitivities/resistance was tested
Results: samples submitted by ICUs were 446 with 302 from devices. Tracheal samples were 189[62.6%] whereas CV tips [30%] and Folleys catheter [4.3%]. Growth positive samples were 219 [72%]. Non fermentors comprised 54 % isolates with Acinetobacter predominating [33%] followed by Pseudomonas [21.8%]. Enterobacteriaceae were 44% with E coli [16%] Klebsiella [12%] Proteus [10.7%] and Citrobacter [5.9%]. Gram positive isolates comprised [n=23] isolates. Oxacillin resistant were [n=4]. Acinetobacters [n=20] Pseudomonas [n=15] and Enterobactericeae [n=18] with Klebsiella [n=12] were resistantto all drugs tested. ESBLs were 14
Conclusion: DAls are a serious threat in ICU. Surveillance Programmers should be carried out under guidance of INICC
ABSTRACT
Breast cancer is the most common type of cancer in women, age 40 - 50 years. It is the second leading cause of cancer deaths i.e about 250,000 women die of this disease every year. The purpose of the study was to evaluate the accuracy, utility and feasibility of Fine Needle Aspiration Cytology [FNAC] in diagnosing breast lesions in association with palpable size of the tumour. It was a descriptive study conducted in the Department ofHistopathology; Services Institute of Medical Sciences and Services Hospital Lahore. The study included 464 patients with palpable breast lesions undergoing fine-needle aspiration cytology during a period of three years from January 2006 to December 2008. Using d - C5 categories of FNAC smears, 281 out 0/464 [60.6%] were categorized as C[2] followed by C[5] 48 [10.3%], there was a significant [P < 0.0001] relationship between palpable size of the breast lesion and cytological category of the specimens. Fibroadenoma was the most frequent [161] [34.6%] benign tumour, C[3] accounted for 9.3% [43 out of 464]. The C[1] - C[5] grading system for FNAC is the most cost - effective and practical out patient procedure for early diagnosis of breast lesions. It is recommended that FNAC should be used as a routine diagnostic method to maximise availability of health care to patients with breast lesions