ABSTRACT
<p><b>OBJECTIVE</b>To analyze the learning curve of gastric bypass procedure on rats model by a single operator.</p><p><b>METHODS</b>From June 2013 to September 2013, two groups (group A and group B) of rats model were performed gastric bypass surgery, 60 rats for each group. Each group was divided into 3 stages according to sequence. The operative time and postoperative survival rate were compared between A group and B group at first, then among stages of each group.</p><p><b>RESULTS</b>There were no significant differences between A and B group in operative time and postoperative survival rate. However, the operative time significantly decreased in group AII( and AIII( compared with AI(, [(78.5±2.5) and (73.3±1.4) with (127.3±3.2) min, P<0.01]. The postoperative survival rate was increased in group AII( and AIII( than in the group AI(, [75%(15/20) and 85%(17/20) with 30%(6/20), P<0.05]. All results of 3 stages in group B was similar to group A.</p><p><b>CONCLUSION</b>For an efficient and stable rate of successful model establishment, the researcher needs to operate about 20 rats to pass the learning curve of gastric bypass procedure.</p>