Head and neck malignancies are mostly from dermatological origin

Head and neck cancer includes epithelial malignancies of the upper aerodigestive tract [UADT], including the paranasal sinuses, nasal cavity, oral cavity, pharynx, and larynx; and, as the sixth most common cancer worldwide, head and neck cancer represents about 6% of solid tumors. Advances in surgery, radiation therapy, and chemotherapy have improved locoregional control, survival, and quality of life. The outcomes of these treatment modalities have shifted the focus of curative efforts from radical ablation to preservation and restoration of function. This evolution has been documented in the pages of Cancer for the past 6 decades. The median age of diagnosis is in the sixth decade of life, and there is a large male-to-female predominance. Although there has been a slight decrease in overall incidence of head and neck cancer over the past two decades, an increase in base of tongue and tonsillar cancer recently has been observed

Surgical management of patients with infective endocarditis: a systematic review

Introduction: Replacement of the heart valves has been spread recently with wide variety of types and surgical techniques. There is, however, no consensus regarding the best type and/or techniques of the surgical treatment of infective endocarditis

Objective: The aim of the systematic review was to evaluate the evidence-based published articles dealt with different types of valve replacement in the management of infective endocarditis

Methods: An electronic search was conducted on the electronic search engine PubMed including Medline. Keywords used for this research included; infective endocarditis, bacterial endocarditis, surgery, valve replacement, outcomes, timing, mortality, relapse and death

Results: Among the screened articles there were a total of 11 articles included for this systematic review. Out of which, there were 6 prospective randomized clinical trials and the remaining 5 studies were prospective clinical trials without randomization

Conclusion: From the findings of this review it can be concluded that the infective endocarditis is still a life-threatening disease requires more efforts for prevention and management. Surgical treatment of infective endocarditis with prosthetic or biologic valves does not differ significantly in outcomes or complications with a little bit higher in complications when using biologic valves