Comment about paraneoplastic syndrome in patients with lung cancer at Department of Respiratory in Bach Mai Hospital from 2003 to 2005

Background: Paraneoplastic syndrome is a rare syndrome on lung cancer patients in Vietnam and in the world. Objective: To define the percentage of the common paraneoplastic syndromes on lung cancer patients and research the clinical and investigations of these syndromes. Subjects and method: A study included 570 patients diagnosed lung cancer based on histopathological and cytological evidences, treated in Department of Respiratory in Bach Mai Hospital from 2003 to 2005. This was a descriptive, retrospective study. Results and conclusions: 19.47% of the patients had common paraneoplastic syndromes. Pierre Marie's syndrome was the most common (65.8%), followed by Schwartz-Bartter's syndrome (25.2%). 64.8% of the patients were 50 to 69 years old, 88.3% were men, 83.8% were smokers. 66.6% of patients were the severe periods. 30.7% of patients were diagnosed histologically adenocarcinoma. 12.8% of patients had Pierre Marie's syndrome, 5.3% had Schwartz-Bartter's syndrome, 1.9% had hypercalcemia of malignancy and 1.9% had thromboembolism.

Studying clinical manifestations of acute exacerbation \r\n', u"of 150 patients with COPD by Anthonisen's classification in \r\n", u'Department of Respiratory of Bach Mai Hospital \r\n', u'

Background: Exacerbation of chronic obstructive pulmonary disease (COPD) is the common complication of COPD and sometimes is lethal cause of patients. Objective: To study clinical manifestations of exacerbation of 150 patients with COPD by Anthonisen's classification at the Department of Respiratory of Bach Mai hospital. Subjects and method: A retrospective, prospective, descriptive study included 150 patients in Department of Respiratory of Bach Mai hospital, from February 2005 to March 2006. Retrospective study included 100 patients and prospective study included 50 patients. Results and conclusions: The male - to - female ratio is 6:1. The average age of patients was 68.85 \xb1 9.45 years. The most of age group was 61 - 70 years. 73.33% patients hospitalized were belonged to type I - this was serious type and similarity of III-IV stage according to GOLD 2003' classification of COPD. 100% of cases hospitalized with dyspnea, 90.6% cough with purulent sputum, 58.7% fever.

Studying on clinical, subclinical manifestations and lung CT-scan images of patients with empyema

Background: Empyema is not rare in Vietnam and in the world. Objective: To study clinical, subclinical manifestations and lung CT-scan images of patients with empyema. Subjects and method: A study included 50 patients of empyema treated in Department of Respiratory of Bach Mai Hospital, from January 2003 to August 2005. This was a retrospective, prospective, descriptive, cross-sectional, controlled study. Results and conclusions: Most empyema commonly occurred in the setting of bacterial pneumonia. Empyema was common in males and the male-to-female ratio was 2.82. The onset of empyema was suddenly with clearly infection syndrome (high fever, increased WBC count, accelerated erythrocyte sedimentation rate), chest pain, and cough. CT images of empyema were ipsilateral; almost empyema was free pleural effusion and moderate in size. Thickening pleura was 72% and located pleura were 42%. Positive culture of pleural fluid was very low (24%). Gram (-) bacteria was predominant (P. Aeruginosa 33.3%, K. Pneumoniae 25%).