A comparative study of YGH index and Wayne's index in the diagnosis of thyrotoxicosis

This study was done during 1992 to 1994. the patients were in-patients of Wards 1 & 2 and those referred from the Nuclear Medicine Department of Yangon General Hospital. they all were clinically thyrotoxic patients confirmed by either high uptake of radioactive iodine or high serum T3 and T4 levels. We took proper history taking and did thorough clinical examination for all patients. Then we recorded the findings and counted the scores for each patient according to YGH index and WAYNE index for diagnosis of thyrotoxicosis. The total numberr of patients studied was 138. Mean age was 36.5 years. The sensitivity of YGHindex was 93.47 percent. The sensitivity of WAYNE index was 89.85 percent. The difference between the sensitivities of two scoring systems was not significant statistically. Therefore, both scoring systems can be applied with the nearly same sensitivity in the clinical diagnosis of thyrotoxicosis.

Association of chronic complications of diabetes mellitus and presence of risk factors

Chronic complications of diabetes are known to be associated with certain risk factors. Once complications develop, they will never regress, denoting that reduction of these factors as much as possible, is the best way to deter the complications. To determine such risk factors, a study was done on diabetic patients with a ample size of 315 from Diabetic Clinic and Ward 1 + 2, Yanton General Hospital. There were 281 NIDDM and 341 IDDM patients. The study on NIDDM patients shows that physical inactivity and age of the patients were associated with the development of retinopathy. The following factors were identified as being associated: hypertension, high serum cholesterol and age of the patient. Smoking is also associated with neruopathy. The possible risk factors for nephropathy were age of patient, hypertension, alcohol and hyper-uricaemia. Hypertension, age of the patient, male sex and pbhysical inactivity were found to be important risk factors for CVA. For IHD, contraceptive pills, physical inactivity and age of patients were possible risk factors. On the other hand, physical inactivity, hypertension, age of patient and duration of disease were important for peripheral vascular disease. Out study spotlihgted that age factor is the mainstay in the development of chronic complications in both NIDDM and IDDM. In NIDDM physical inactivity predisposes to retinopathy and atherosclerotic complications. Hypertension enhances neuropathy, nephropathy, CVA and peripheral vascular disease. However, in IDDM, the duration of diabetes and fasting blood sugar levels are significant risks in the development of retinopathy and nephropathy.