ABSTRACT
BACKGROUND: Percutaneous vertebroplasty and percutaneous kyphopiasty are widely used minimally invasive surgery for vertebral compression fractures, spinal primary tumor and spinal metastasis. However, there were no bibliometric studies and mapping knowledge domains study regarding percutaneous vertebroplasty and percutaneous kyphopiasty. OBJECTIVE: To summarize and identify the papers related to percutaneous vertebroplasty and percutaneous kyphopiasty, and mapping knowledge domains of percutaneous vertebroplasty and percutaneous kyphopiasty. METHODS: Web of Science was retrieved for studies published from 1985 to 2018. The key words were TS = vertebroplasty OR kyphopiasty. All data were input into the Microsoft Excel 2016 and VOSviewer to identify publication number, publication year, publication country, publication organization, publication source, author, sum of times cited (including and excluding self-citation), average cited times and H-index. VOSviewer software was used to analyze the co-cited references, the co-cited authors and the co-occurrence of key words, and mapping knowledge domains. RESULTS AND CONCLUSION: (1) The research regarding percutaneous vertebroplasty and percutaneous kyphopiasty is one of the important research areas in spine surgery research domains. (2) USA dominates the research regarding percutaneous vertebroplasty and percutaneous kyphopiasty. The qualities of papers from Switzerland and England are relatively high while those from China and Italy are relatively low. (3) Some of the organizations that published most papers and high-quality papers include Mayo Clinic, Suzhou University, Johns Hopkins University, Cleveland Clinic Foundation and University of Bern. (4) Some of the journals that published most papers and high-quality papers include SPINE, EUROPEAN SPINE JOURNAL, AMERICAN JOURNAL OF NEURORADIOLOGY, JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. (5) Some of the authors that published most papers and high-quality papers include YANG HL, KALLMES DF, PFLUGMACHER R, DERAMOND H, CHIRAS J, FERGUSON SJ and MASALA S. (6) The key contents of percutaneous vertebroplasty and percutaneous kyphopiasty include osteoporotic vertebral compression fracture, tumor, bone cement, surgery, biomechanics and refracture.
ABSTRACT
Objective:To identify the characteristics and risk factors of the refractures after percuta-neous kyphoplasty ( PKP) and percutaneous vertebroplasty ( PVP) .Methods:A retrospective analysis of 148 patients who had undergone PKP or PVP between March 2006 and October 2013 inPeking University People’ s Hospital was conducted.In the study, 29 patients with 42 refractured vertebra and 119 patients without refracture were included.All the patients were observed for a time of (34.4 ±26.8) months. Clinical, imaging and procedure related factors ( gender, age, height, weight, body mass index, the level of the injured vertebra, the time interval between the procedure and the refracture, the level of the refractured vertebra, the bone cement volume injected, performed PKP or PVP,performed unilateral or bilateral, the percentage of anterior vertebral height restoration, the correction of the Cobb angle, cement diffusion, bone mineral density, presence or absence of diabetes mellitus, history of fractures of the whole body, anti-osteoporosis treatment, cement leakage) for each group were analyzed by Cox propor-tional hazards regression analysis.Results:Of all the patients,16 (55.17%, 16/29) had refractures in the adjacent vertebra, and 13 (44.83%, 13/29) had refractures in the nonadjacent vertebra.Refrac-tures within 3 months accounted for 31.03%(9/29) of all the refractures, and within 1 year accounted for 55.17%(16/29).Both older age (P=0.027, HR=1.051, 95%CI=1.006-1.098) and a his-tory of fractures of the whole body (P=0.012, HR=0.386, 95%CI=0.184-0.812) were statistical-ly significant as the independent risk factors for predicting refractures.Others were not associated with re-fractures ( P>0.05) .Conclusion:Older age and a history of fractures of the whole body are the inde-pendent risk factors of the refractures after PKP and PVP.The mechanism of the refractures after PKP and PVP is mainly the natural development of osteoporosis.