ABSTRACT
1. The frontal sinuses of 250 skulls of Chinese male adults were investigated. Ac-cording to the number of the frontal sinuses, the skulls were classified into five types. Type Ⅰ. no frontal sinus. Type Ⅱ. one frontal sinus (either left or right). Type Ⅲ. two frontal sinuses (one on each side). Type Ⅳ. three frontal sinuses (two left, one right, & vice versa). TyPe Ⅴ. four frontal sinuses (two on each side). 2. The degrees of superior, lateral and posterior extensions of the frontal sinuses inmost cases were grossly symmetrical. 3. It was found that two frontal sinuses were extended posteriorly over the orbitto near the greater and lesser wings of the sphenoid bone. 4. The degree of prominence of the superciliary arches was neither the indicationof the presence of the frontal sinuses nor the estimation of its extension or size. 5. The thickness of the anterior wall of the frontal sinuses was within 0.8--3 mm(89.4% on the left, 84.6% on the right), and the thickness of its septum fluctuated be-tween 0.1--2 mm (70.4%). The septa of all metopic skulls were divided into two partsby the suture. 6. The invading cells and the recesses of the frontal sinuses were studied, classifiedand discussed. 7. The position of the openings of the naso-frontal duct was as follows: 1. drain-age into the ethmoid infundibulum 49.5%. 2. drainage into the frontal recess 26.2%. 3.drainage into the frontal pit 20.5%. 4. drainage into the supra-bulla region 3.8%.
ABSTRACT
Substance P-like immunoreactive (SP-li) cell bodies and processes and their synaptic relations with other neural elements in the nucleus raphe magnus (NRM) of rats were studied by electron microscope. The results showed that SP-li neurons are fusiform, oval and multipolar cells which distribute evenly over the nucleus. Immunostaining was present in the cytoplasmic matrix and membranes of mitochondria, endoplasmic reticulum and vesicles. Both unmyelinated and myelinated SP-li axons are found in the NRM. SP-li dendrites are numerous in the NRM. SP-li dendrites and somata are contacted by a variety of round, flat and granular vesicle-containing terminals. A central SP-li dendrite receivie convergent inputs from unlabelled axonal boutons is frequently seen in the NRM. SP-li terminals are presynaptic to the unlabelled dendrites, also some SP-li terminals are apposed or presynaptic to SP-li dendrites. Axo-axonic (SP-li) synapses were found in the NRM. The unlabelled presynaptic boutons contain clear round vesicles or mixed with granular vesicles. A central SP-li terminalis contacted by several unlabelled terminals is also found in the NRM.
ABSTRACT
Nucleus raphe dorsalis (RD) plays an important role in acupuncture analgesia. We carried on further studies on the projections of RD from the forebrain and brain stem of the cat by using a horseradish peroxidase (HRP) retrograde axonal transport method.We have observed the labeled neurons in layer Ⅴ of the proreate gyrus, area prepyriformis, nucleus lateral habenular, and hypothalamic areas (preoptic, lateral, medial and posterior areas) when HRP was injected into the rostral part of the RD. The labeled neurons were giant pyriform in shape in prereate gyrus and area prepyriformis and various shapes in the lateral habenular and hypothalamic areas.We have also found the labeled neurons in the periaqueductal gray matter, locus coeruleus, lateral and medial parabrachial nuclei, other raphe nuclei (n. centralis superior, n. raphe magnus and n. linearis intermediate) and reticular formation of the brain stem when we injected HRP into the caudal part of the RD.This present results confirm that the fibers project to the RD directly from the forebrain cortex (proreate gyrus and area prepyriformis), latral habenular nucleus hypothalamic areas, periaqueductal gray matter, locus coeruleus and other raphe nuclei. We also have found that the afferent projections to the rostral part of the RD and the caudal part of the RD had different origins, that is, the rostral part receives fibers from the forebrain and the caudal part receives fibers not only from the forebrain, but also from the brain stem. The study provided a foundation for explaining acupuncture analgesia and physiological functions of RD.
ABSTRACT
A total of 30 cats were used in this experiment.The nucleus raphe magnus wasinjected with 0.1～0.3?l of 25～50% HRP solution(RZ:2.4～3.1).Two or three daysafter operation,the animals were killed and then perfused with the fixing fluid.Thebrainstem and spinal cord were sectioned serially on a freezing microtome and treatedaccording to the method of retrograde axonal transport of horseradish peroxidase.Parts of the sections were counterstained with toloidine-blue.The labelled neuronswere examined microscopically under bright-field and dark-field illumination Thelabelled neurons were distributed as follows.After injections of nucleus raphe magnus,a few labelled neurons were foundin the medial part of parafascicular nucleus of the thalamus.A greater numbers oflabelled cells were consistently found in the ventrolateral area of the central greymatter of the midbrain.The dorsal nucleus of the midbrain raphe had a few labelled neurons.The HRPpositive neurons were found in the nucleus Darkschewitsch,mesencephalic reticularformation,nucleus reticularis gigantocellularis,nucleus reticularis paramedianus,nucleus vestibularis medialis and nucleus vestibularis lateralis.In some cases a fewlabelled cells were also seen in the posterior area of hypothalamus,nucleus posteriorcommissure,nucleus tegmentalis dorsalis,superior collicus,nucleus annularis,reticularformation of the pons,nucleus nervi facialis and nucleus gracilis.In summary,the present studies show that the afferent connections of nucleusraphe magnus are widely concerned with the structures of the pain control.Itsuggests that the nucleus raphe magnus is an important relay station for pain control.