Predictive and Prognostic Roles of Pathological Indicators for Patients with Breast Cancer on Neoadjuvant Chemotherapy / 한국유방암학회지

Research progress on dry eye imaging technology / 国际眼科杂志(Guoji Yanke Zazhi)

@#In recent years, advances in dry eye imaging technology have not only been reflected in the ability to evaluate measurements based on clinical practice, but also to define new parameter data while ensuring the objectivity of measurement results. On this basis, it is beneficial to in-depth analysis of structural and functional parameters for diseases of dry eye. This article provides a brief overview of techniques such as tear film interferometry, optical coherence tomography, meibomian gland imaging, non-invasive rupture time, thermal imaging and optical quality assessment, and confocal microscopy used in dry eye diagnosis and treatment.

Expression of NOD2 and NLRP3 in the articular cartilage of a rabbit model of osteoarthritis established by arthrorisis using plaster cast / 中国组织工程研究

BACKGROUND: Nucleotide-binding oligomerization domain (NOD)-like receptor plays an important role against inflammatory responses caused by pathogens and non-pathogens, as well as in the initial stage of autoimmune response. Meanwhile, NOD2 and NOD-like receptor protein 3 (NLRP3) are the representative proteins of NOD-like receptor family. OBJECTIVE: To detect the expression of NOD2 and NLRP3 in a rabbit model of osteoarthritis. METHODS: Thirty New Zealand rabbits were randomly divided into six groups (n=5 per group), including five experimental groups (2, 4, 6, 8 and 10 weeks) and one control group. The model of osteoarthritis was established by fixing the left knee joints using plaster cast, and were sacrificed at postoperative 2, 4, 6, 8 and 10 weeks. The controls received no intervention, and were killed at 10 weeks postoperatively. The left distal femur articular cartilage was taken for safranin-fast green staining. The pathological changes were evaluated by Mankin's scores, and the expression levels of NOD2 and NLRP3 were detected by immunohistochemistry. RESULTS AND CONCLUSION: The Mankin's scores in the experimental groups were significantly higher than those in the control group (P <0.01). Moreover, the scores in the experimental groups were significantly increased with time (P < 0.01). The expression levels of NOD2 and NLRP3 in the chondrocytes were also increased with time (P < 0.01). These results indicate that the expresison of NOD2 and NLRP3 in the cartilage cells is positively correlated with the pathological changes of osteoarthritis, which may be through promoting apoptosis in cartilage cells, thus accelerating the development of osteoarthritis.

Authors of Science and Technology Article Should Use Standard Science and Technology Term Actively / 中国康复理论与实践

@#Standardizing and unifying science and technology term is important to improve science and technology progress, support development of branch of learning and communicate with foreign. While, there are some deficiency in extending and using standard science and technology term in domestic, all science and technologyh works should use standard science and technology term actively.

Familiar Problems in Academic Papers of Rehabilitation Medicine / 中国康复理论与实践

@# Following problems such as scientificalness absent in study design,incorrect data,paper title not accorded with fact,unreasonable personalization and style or manner of writing not oneness or coherence are often seen in academic papers of rehabilitation medicine.The authors of papers should pay attention to these problems.