Investigation on the efficacy of postoperative analgesia of Oxycodone-acetaminophen for total hip replacement / 中国基层医药

Objective To investigate the analgesic effect of oxycodone-acetaminophen tablet on total hip replacement(THR).Methods 93 patients were chosen and randomly divided into two groups:oxycodone-acetaminophen group(experimental group)and placebo group(control group).Analgesic effect of postoperation and adverse effects were observed.Results Compared with the control group,analgesic effect of postoperative 6h,24h,48h and 72h in experimental group had statistically significant difference(all P＜0.05).Compared with the control group,adverse effect in experimental group had no statistically significant difference(all P＞0.05).Conclusion Oxycodoneacetaminophen in THR postoperative patients had obvious analgesic effect and had no obvious side effects.