ABSTRACT
Background and Objectives: The long history of traditional medicine clearly demonstrates the role of nutrition in the prevention andtreatment of the disease. Of particular importance in modern scientific medicine is the simultaneous use natural biologically activecomplexes and mediccines. The objective of this study is to provide clinical evidence of the effectiveness and functional orientation of a newtype of biologically active additives (BAA) in the patients with vegetative vascular dystonia and chronic cerebrovascular disorder.Methodology: The principles of the modern science of nutrition on the role of individual macro-and micronutrients, and minor componentsof food in the correction of metabolic disorders form the methodological basis of the research. Results: The biologically active additive"Sophia" was introduced in the diet of the patients for 4 weeks at a dose of one tablet, in combination with 50 mg of Trental per day (the 1stmain group). The 2nd main group received an additional "Guta-Viva" additive. The 3rd (control) group received Trental only, at theprescribed dosage. The use of BAA had a positive effect on the relief of disease syndromes, and improved overall health. Conclusion: Theantioxidant effect of the specialized product, as well as the improvement of metabolic processes in the brain, was noted. A conclusion wasmade that the test product can be an effective remedy in the treatment of moderately grave vegetative-vascular dystonia. BAA is welltolerated by the patients and does not cause side effects.
ABSTRACT
The prescription composition and the technology of a new type of specialized product - biologically active additive BAAhave been scientifically grounded. The pharmacological properties and functional orientation of the active principles of theformulation components of the dietary supplements were studied, which made it possible to determine the quantitative andqualitative composition of the formulation which has a synergistic effect on metabolic processes in the presence ofdeforming osteoarthrosis: bamboo extract, glucosamine and chondroitin, aloe vera extracts, leaves and grape seeds, vitaminand mineral composition with green tea extract, and the antioxidant complex "Cifrol-5". A production technology providinghigh consumer performance for the developed product was approved. Clinical trials involving two groups of women aged44-49 with deforming osteoarthritis of the knee joints confirmed the functional properties of the complex. The first groupreceived the BAA, the second was a control group. Changes in the control indicators were registered after dietary therapyor in clinically significant periods of patient recovery. The control indicators were joint soreness, skin, hair, and nailcondition, and the recovery time of postoperative sutures. The complex application of diet therapy and the basic treatmentfor dystrophic joint diseases and the rehabilitation measures of the postoperative period were shown to be effective. Inpatients, joint pain and pain index decreased, the fragility of nails and hair was reduced, the microcirculation of the nail bedimproved, and the healing time of the surgical sutures decreased. The consistency of quality indicators and consumerperformance was ensured by production certifications for the developed products within the requirements of internationalstandards of the ISO 9001 and 22000 series and GMP rules.