ABSTRACT
Objective To explore the characteristics of emotional memory in adolescent with anxiety disorders.Methods Totally 40 adolescent patients with anxiety disorders who met the DSM-5 diagnostic criteria were selected as the anxiety disorder group,40 normal adolescents matched with anxiety disorder group in terms of gender,age and education level served as the control group.All subjects of the two groups were implemented by emotional memory test task.Results (1) In emotional memory test,the negative picture score of adolescent anxiety disorder group(2.10±0.75)was significantly lower than that of control group (2.76±0.92) (t=-3.29,P＜0.05).There were no significant difference in positive and neutral picture scores between the two groups(P＞0.05).(2)Compared with control group,the positive picture,neutral picture and total recognition accuracy of adolescent anxiety disorder group both were significantly decreased ((0.24±0.09) vs (0.33±0.08),(0.22±0.10) vs (0.32±0.14),(0.25±0.08) vs (0.33±0.09)) (t=-4.28,-4.28,-3.85,all P＜0.05).There was no significant difference in negative picture recognition accuracy between the two groups (P＞0.05).In adolescent anxiety disorder group,there were significant differences in the correct recognition rates of negative pictures,positive pictures and neutral pictures in anxiety disorder group (F=3.39,P＜0.05),while there was no significant difference in the control group (F=0.04,P＞0.05).(3) The positive picture recognition accuracy and total recognition accuracy in adolescent anxiety disorder group were negatively correlated with Hamilton Anxiety Scale (HAMA) (F=0.04,P＜ 0.05).Conclusion Adolescent anxiety disorders exist in emotional memory defects,and its positive emotional memory deficit is negatively correlated with the severity of anxiety.
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Objective To explore whether the ability of intertemporal choice is impaired in schizophrenic patients and in their unaffected siblings.Methods Twenty-five schizophrenia patients,twenty-five unaffected siblings of patients and thirty healthy controls were recruited in the study."Delay-discounting" task and a battery of cognitive neuropsychological assessment were used to examine the intertemporal decision-making.Results (1) the value of k was ((0.005±0.009 in schizophrenia,0.011±0.014 in unaffected siblings and 0.024±0.029 in healthy controls,respectively.There was significant difference in k value among these three groups (F=9.487,P＜0.001).There were significant differences in k value between patients group and healthy controls,and between unaffected siblings and healthy controls (P＜0.05).There was no significant difference between schizophrenia and their unaffected siblings (P＜0.05).(2) Pearson correlation analysis not showed any relationship between neuropsychological test and the value of k.Conclusion The ability of intertemporal choices is impaired in schizophrenia and their unaffected siblings to a great degree.
ABSTRACT
Objective To explore whether the ability of intertemporal choice is impaired in schizophrenic patients and in their unaffected siblings.Methods Twenty-five schizophrenia patients,twenty-five unaffected siblings of patients and thirty healthy controls were recruited in the study."Delay-discounting" task and a battery of cognitive neuropsychological assessment were used to examine the intertemporal decision-making.Results (1) the value of k was ((0.005±0.009 in schizophrenia,0.011±0.014 in unaffected siblings and 0.024±0.029 in healthy controls,respectively.There was significant difference in k value among these three groups (F=9.487,P＜0.001).There were significant differences in k value between patients group and healthy controls,and between unaffected siblings and healthy controls (P＜0.05).There was no significant difference between schizophrenia and their unaffected siblings (P＜0.05).(2) Pearson correlation analysis not showed any relationship between neuropsychological test and the value of k.Conclusion The ability of intertemporal choices is impaired in schizophrenia and their unaffected siblings to a great degree.
ABSTRACT
Objective To investigate whether there are changes in the ability of intertemporal choices in migraine sufferers. Method Thirty migraine sufferers and thirty healthy controls were investigated by Delay?discount Test. Results (1)The ratio of later?large (LL) choice in migraine suffers((18.15± 17.53)%) was significantly lower than that in the healthy controls((35.37±20.70)%),and the difference was statistically significant(t=3.31, P<0.05).Under the immediate option for now selection conditions and no immediate option for not?now selection conditions,the ratio of later?large (LL) choice in migraine suffers ((18.33±21.00)% ,(17.96±18.09)%) was also significantly lower than that in the healthy controls ((35.56±21.52)%,(35.19±22.05)%),and the difference was statistically significant(t=3.31, P<0.05;t=3.14, P<0.05).(2) Pearson correlation analysis showed that the Stroop Test of migraineurs was positively correlated with LL selection ratio under now conditions (r=0.49, P=0.006) and total LL selection (r=0.42, P=0.021) . Conclusion The ability of intertemporal choices in migraine sufferers has been impaired,which is correlated with executive function.