ABSTRACT
Estrogen plays an important role in the genesis and growth of gynecological tumor. Transvaginal sonography assessment of endometrial status is most commonly used in menopausal women to investigate significant findings before hormone replacement therapy (HRT) in pre- and postmenopausal women. One hundred and eighty-six pre- and postmenopausal women with no known history of HRT were transvaginally measured for endometrial thickness of the uterus and pelvic organs. Their age (mean ± standard deviation) was 51.4 ± 5.8 years (range 38 – 75 years); 48.4% were in pre-menopause group, the rest were in post-menopause group. In the latter group, most of them (64%) had had amenorrhoea for 1-5 years. The endometrial thickness in post-menopause group was 4.7 ± 3.4 mm (0 – 22 mm). Myoma was found in 10 cases (5.4%) and ovarian cyst in 6 (3.2%). There were six cases (3.2%) of endometrial hyperplasia. Transvaginal sonography would be useful in the evaluation of endometrium and pelvic organs before HRT