Subject(s)
Humans , Male , Aged, 80 and over , Angioplasty, Balloon, Coronary/adverse effects , Wounds, Penetrating/etiology , Wounds, Penetrating/therapy , Stents/adverse effects , Coronary Vessels/injuries , Heart Injuries/etiology , Heart Injuries/therapy , Treatment Outcome , Cardiac Tamponade/etiology , Cardiac Tamponade/therapyABSTRACT
Acute right ventricular failure after cardiac surgery occurring in the first postoperative hours is associated with a bad prognosis. We have used a centrifugal pump either for ¡eft, right or biventricular assistance. However, the use of this device for pure right ventricular assistance is rare. We report a 30 year-old female undergoing a mitral valve replacement and a 42 year-old male undergoing a cardiac transplantation, who had a successful right ventricular assistance using a centrifugal pump, due to a failing right ventricle, as the result of insufficient myocardial protection and severe pulmonary hypertension. These two cases illustrate the value of the mechanical ventricular assist device for the treatment of right heart failure.
Subject(s)
Adult , Female , Humans , Male , Heart-Assist Devices , Ventricular Dysfunction, Right/therapy , Acute Disease , Epinephrine/therapeutic use , Heart Failure/therapy , Hypertension, Pulmonary/therapy , Norepinephrine/therapeutic use , Time Factors , Vascular Resistance/drug effects , Vasoconstrictor Agents/therapeutic useABSTRACT
Background: The optimal dose of Streptokinase in the treatment of acute myocardial infarction is not well established. Apparently, the thrombolytic efficacy would not increase with doses over 750.000 units. Aim: To compare the effectiveness and safety of treatment with low doses of Streptokinase, ranging from 500.000 to 750.000 units, in patients with ST elevation acute myocardial infarction. Patients and methods: From September 1993 to September 1998, the GEMI register of patients with acute myocardial infarction, was carried out in 37 hospitals, incorporating 4,938 patients. Of these, 1,631 patients received streptokinase. According to the administered dose of Streptokinase, patients were divided in two groups: 1,465 patients who received 1.5 millions U in 60 minutes (classical therapy group), and 166 patients with ischemic chest discomfort and either ST-segment elevation or left bundle-branch block on the electrocardiogram, who received 500.000 to 750.000 U streptokinase administered in no more than 30 minutes, with heparin, within 0 to 6 hours of symptom onset. Successful reperfusion, mortality, complications, and hospital outcome was evaluated in both groups. Results: The low dose group of patients had a better reperfusion criteria profile. No differences between groups were observed in patient evolution, mortality, maximum Killip classification, post myocardial infarction heart failure, ischemic complications, arrhythmias or mechanical complications. Conclusions: These results suggest that streptokinase in low doses is at least as effective as classical therapy, in the treatment of ST elevation acute myocardial infarction.
Subject(s)
Aged , Female , Humans , Male , Middle Aged , Fibrinolytic Agents/administration & dosage , Myocardial Infarction/drug therapy , Streptokinase/administration & dosage , Thrombolytic Therapy , Chi-Square Distribution , Creatine Kinase/blood , Electrocardiography , Fibrinolytic Agents/adverse effects , Heparin/administration & dosage , Heparin/adverse effects , Myocardial Infarction/complications , Myocardial Reperfusion , Pain Measurement , Prospective Studies , Risk Factors , Streptokinase/adverse effects , Thrombolytic Therapy/adverse effects , Treatment OutcomeABSTRACT
Se presenta la experiencia en transplante cardíaco del Hospital Dr. Gustavo Fricke de Viña del Mar desde la creación del Comité de Enfermedades Cardiorespiratorias Terminales en 1998. Actualmente hay 9 pacientes en control. Se analizan los resultados a corto y largo plazo, la terapia utilizada y las complicaciones más frecuentes y su manejo