Pharmacological effects of Silymarin extracted from introduced milk thistle fruits (Silybum marianum (L.) Gaertn.)

Study on the pharmacological effects of Silymarin extracted from introduced milk thistle fruits (Silybum marianum (L.)) collected at Sa Pa and Ha Noi in June 2002. Results: the silymarin product had chronic anti-inflammatory effects in experimental tumor model, inhibited formation of granuloma with the rate of 28.69% compared with control rats; had hepatic protection effect, decreased GPT enzyme activity and serum bilirubine of rats with 36.19% and 38.18%, respectively, in CCl4 poisoned model compared with control rats; increased bile flow up 32.25% compared with this before receiving silymarin and 49.88% compared with rats without drug, but didn’t change the bile quality

Study on hepatoprotective effect of an extract from Plantago asiatica L

Extract F1 from Plantago asiatica L. provided hepatoprotective activity, decreased liver GPT enzyme (91.7%) and serum bilirubine (25.8%) in model of CCl4-induced cirrhosis mice, versus control group. Extract F1 had hepatoprotective activity, decreased liver GPT enzyme and serum bilirubine in model of CCl4-induced cirrhosis mice, versus control group (27.5% and 19.4%, respectively). Extract F1 had anti-oxidant activity, decreased liver MDA level by 21.2%, inhibited cirrhotic process, decreased collagen level by 26.5% versus control group