ABSTRACT
Background: Diabetes mellitus is considered as most prevalent non-communicable disease throughout the world. It is associated with many complications. Hearing loss among diabetics is a recent concern, its magnitude and pathophysiology are not yet clearly defined. Aim and Objectives: The present study aimed to determine the relation between diabetes and hearing loss. Materials and Methods: The present study was conducted with 200 diabetes mellitus patients aged between 20 and 50 years, selected from endocrinology outpatient department, SCB Medical College and Hospital, Cuttack. Participants were subjected to pure tone audiometry at the department of ENT. Two hours PGBS (75 g) value was collected. Results: About 58% of the participants were detected with sensorineural hearing loss. There was a significant association of hearing loss with the duration of diabetes and glycemic status (with P < 0.05). Conclusion: The hearing loss found among diabetics showed strong association with the duration of the disease and the glycemic status. If detected earlier in its course, long-term complications of hearing can be avoided.
ABSTRACT
For a female, type 2 diabetic patient, with 4 years duration of diabetes, Exenatide (Byetta) was prescribed as glycaemic control was not satisfactory along with Glimepiride and Metformin. She had gastrointestinal disturbances, since the first day of the injection. From the eighth day she developed signs of acute pancreatitis which was confirmed with CT-Scan and biochemical investigations. Byetta was withdrawn, the patient was treated for acute pancreatitis and the symptoms subsided.
Subject(s)
Acute Disease , Diabetes Mellitus, Type 2/drug therapy , Drug Interactions , Female , Humans , Hypoglycemic Agents/adverse effects , Injections, Subcutaneous , Insulin/therapeutic use , Metformin/administration & dosage , Middle Aged , Pancreatitis/chemically induced , Peptides/adverse effects , Sulfonylurea Compounds/administration & dosage , Venoms/adverse effectsABSTRACT
The effects of an organophosphate insecticide. dimecron. has been studied on certain haematological parameters, viz., haemoglobin concentration, RBC number, haematocrit, O2 carrying capacity of blood, etc. of Heteropneustes fossilis following exposures to the LC50 for 24 h and 96 h and 1/10 and 1/50 parts of 96 h LC50 for 90 days. There was a significant decrease in the Hb%, RBC number, HCt% and O2 carrying capcity of blood. But, there was significant increase in the MCH and MCV values following both acute and chronic exposures. The results indicate possible induction of anaemia in the exposed fish.