ABSTRACT
Many antineoplastic drugs are known to be carcinogenic, teratogenic and mutagenic to humans. There is thus a potential risk due to occupational exposure to cytotoxic drugs (CDs). Nurses and pharmacists are the main groups that are exposed to these drugs in the ambulatory care and hospital settings. An analytic cross sectional study was here carried out in order to evaluate the level of knowledge of nurses on the health effects and the routes of exposure to CDs, to clarify the protective measures while handling these agents and to determine the influence of this knowledge on clinical attitudes, behaviour and actual usage of safety measures. The level of knowledge of the nurses concerning antineoplastics was not satisfactory. Findings for nurses' safety behaviour and usage of recommended health safety measures showed that, notwithstanding the rules and regulations pertaining to CDs, nurses did not comply with them fully. In service training is a very effective tool to increase the level of knowledge. This study also revealed the necessity for improvement of the working environment and the availability of appropriate protective equipment.