ABSTRACT
Objective: To establish the hormonal, metabolic and clinical profile for Saudi women with polycystic ovary syndrome [PCOS]
Design: This is a prospective, cross-sectional study conducted at the University Hospital. All women were seen at the gynecology clinic. One hundred women aged between 18 and 45 years were included in the study; 50 women with polycystic ovary disease [PCOS] comprised the study group and 50 women without PCOS comprised the control group. The hormonal, metabolic and clinical profiles were assessed for both groups
Results: There are significantly higher levels of luteinizing hormone, prolactin, free testosterone dehydroepianosterone sulfate, 17 alpha-hydroxy progesterone and fasting insulin in the study group. There were no differences in the levels of total testosterone, estradiol and cortisone levels between both groups. The levels of follicular stimulating hormone and sex hormone binding globulin were significantly lower in the study group. There were no differences in the blood sugar level, cholesterol, triglycerides and low- and high-density lipoproteins. The womens' ages, body mass index, blood pressure, uterine dimensions and endometrial thickness were similar in both groups. The size of both ovaries was significantly greater in the study group. There were more follicles in the ovaries of the study group
Conclusion: Hormonal profile of Saudi women with PCOS was similar with what is already published in the medical literature. But, despite the fact that Saudi women with and without PCOS are overweight, they do not suffer from raised blood pressure and metabolic syndrome; this may be due to the fact that women included in this study were relatively young and the sample size might be too small to draw effective conclusions
ABSTRACT
The aim of this study was to determine the incidence of singleton preterm breech babies born in a teaching hospital, and to study the influence of the mode of delivery on perinatal outcome in preterm births with breech presentation. A retrospective analysis from the medical records of patients who had preterm singleton breech delivery [24 - 36 weeks gestation] was undertaken in a tertiary care hospital in the Eastern province of Saudi Arabia between January 1992 and December 2001. All the patients with intrauterine fetal death, multiple pregnancies and lethal congenital fetal malformations were excluded from the study. Intrapartum and neonatal morbidity and mortality in vaginal versus cesarean delivery groups were the main outcomes measured. Of 24, 708 deliveries that occurred in the hospital during the period of study, there were 195 preterm singleton breech deliveries, giving an incidence of 0.08%. One hundred and forty-eight [75.9%] patients delivered vaginally and did not have any medical or obstetric complications. Forty-seven [24.1%] patients underwent caesarean section. While the neonatal morbidity was similar in the two groups, the neonatal mortality was significantly higher Jar vaginal delivery than cesarean section [p<0. 00069]. In view of the significantly higher neonatal mortality found in vaginal delivery the present study favors abdominal delivery for a singleton preterm breech fetus