ABSTRACT
Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high prevalence of anti-HAV (74.8%) was observed in the study population; the whole study population was found positive for anti-HAV by the age of 25 years. On performing the cost-benefit analysis, it was found that the cost for vaccination with screening for anti-HAV was almost three times cheaper than vaccination without screening. Thus, in the present socioeconomic condition of Bangladesh, a policy based on screening for HAV antibody before vaccination is recommended.
Subject(s)
Adolescent , Adult , Bangladesh/epidemiology , Child , Child, Preschool , Communicable Disease Control/methods , Cost-Benefit Analysis , Female , Hepatitis A/epidemiology , Hepatitis A Antibodies/blood , Hepatitis A Vaccines/administration & dosage , Hepatitis A virus/immunology , Humans , Immunoglobulin G/blood , Immunoglobulin M/blood , Infant , Male , Mass Screening , Seroepidemiologic Studies , Young AdultABSTRACT
Traumatic ventricular septal defect (VSD) is a very uncommon condition, especially in association with blunt chest trauma. A healthy young adult was diagnosed as a case of VSD one week after a road-traffic accident. History and other medical records suggest it was an acquired post-traumatic VSD. Thus, all patients of blunt chest trauma deserve close cardiac evaluation.