ABSTRACT
Background:The ophthalmological problems occur in approximately half of the patients with advanced HIV infection when the CD4 T cell count is usually well below 50/ul and the increasing number and prolonged survival of AIDS patients means that the ocular lesions associated with this syndrome will become more frequent problem. Material And Methods:This was a case series study with no controls. All HIV positive patients were included in this study with or without ocular involvement.50 known HIV positive cases attending OPD and/or admitted in GM and Associated Hospitals, KGMC, and who were willing to take part in study were enrolled after proper counselling.Detail history of the cases is taken including personal data, occupation, history of any risk factor, detail history of systemic disease and ocular symptom with their duration and course.Results:In our study 33 patients did not have ocular symptoms and signs and the remaining 17 patients were found to have ocular involvement. Among them 6 patients were asymptomatic, but they had ocular signs. Amongst various symptoms 7 patients presented with diminution of vision, one had headache, other visual symptoms including watering itching and foreign body sensation were found in 5 patients. Conclusion:More than half of the cases in this study were either illiterate or had attended primary schooling and mostly from rural area. In view of this there is a need to intensify primary health education programme and awareness about AIDS through mass media and education regarding adaptation of safe sexual practices. The role of Govt. program and various NGOs has become more important in this respect to restrict this 21stcentury epidemic.
ABSTRACT
Introduction: Stroke is amongst the leading causes of death exceeded only by heart disease and cancer. Those who survive are usually left with permanent disability. Cerebral infarction is responsible for about 80 percent of all strokes, primary intra-cerebral haemorrhage for 10 percent, subarachnoid haemorrhage for 5 percent and 5 percent cases are due to uncertain causes. Predictors of prognosis in primary intraparenchymal haemorrhage have been evaluated in numerous studies. Objective: To observed the effect of different sizes of hematoma and utilizing them, if feasible as a marker of prognostic significance. Material and methods: In this study we observed 60 patients from the time of admission till 30th day in various wards of Department of Medicine RIMS with hypertensive intra-cerebral haemorrhage, during the period of 2008-2009. A simple method of measuring the volume of haematoma (in cc) on the CT scan is by using the following formula: A*B*C A = longest diameter of the haematoma (in cm.), B = Diameter perpendicular to A (in cm.), C = Height (in cm) which is measured by No. of slices showing the haematoma x thickness of each slide. Result: Total 60 patient were taken into study out of which 33(55%) were alive and 27(45%) were dead in 30 days follow up. In our study, 38 were male and 22 were female out of 38 male 22(66.66%) were alive and 16 (59.2%) dead and in 22 female 11(33.33%) were alive and 11 (40.7%) were dead. Outcome with volume of ICH using the χ2 had shown significant correlation (p < 0.005) with GCS at the time stroke onset (P<0.01), IVH/VE (P<0.01), midline shift test (P<0.01), B.P. at the time of admission (P<0.01). Conclusion: In these study patients with hematoma volume exceeds 60 cm3, the mortality was 100%. Mean volume of hematoma in our study was 35.21 cm3.