ABSTRACT
Thirty four patients with borderline and frankly malignant ovarian tumours treated primarily with conservative surgeries, were studied. There were 8 cases of borderline tumours and 26 cases of frank malignancy, with 19 cases of epithelial cancers and 6 cases of malignant germ cell tumours. All the conservative surgical procedure were not adequate due to unrecognition of the malignant lesions. Postoperative chemotherapy was inevitably necessary in all. There were two recurrences in this series, one clear cell adeno-carcinoma who expired with disease and one immature teratoma who still survived after complete surgery and successful chemotherapy. The outcome in this study reassures that adequate conservative surgery in a woman with a unilateral borderline malignancy or malignant ovarian tumours can perform further childbearing, however a close follow up must be possible.
ABSTRACT
Twelve patients with ovarian common epithelial cancer stage III, IV were treated by post operative chemotherapy; combination of cyclophosphamide, adriamycin and cis-diamminedichloroplatinum. Their revealed overall response rate was 83.3%, clinical complete remission was 66.6%, with a follow-up period of 10.0-23.5 months, and was negative on second look operation 83.3%. The response rate was 77.7%, for residual cancer > 5.0 cm. with a clinical complete remission 55.5%, and was negative on second look operation 66.6%.