ABSTRACT
Background and Objective: colorectal cancer is the most common cancer of GI and 2nd most common cause of cancer death in the world. The purpose of this study was to determine epidemiologic aspect and tumor characteristics of colorectal cancer for patients and compare them in young [<50 yr] and older [>50 yr] patients
Materials and Methods: in this cross-sectional study during 3 yr the samples of malignant colorectal cancer presented in Gorgan endoscopy and pathologic centers were collected. Data evaluated by statistically method
Results: there were 101 cases of malignant colorectal cancer. 61 cases were male and 40 cases were female. The mean age was 56+/-13.65 yr. 13.9% of patients were <40 yr. The type of tumor in 94% was adenocarcinoma, 2.9% lymphoma and 2.9% undifferentiated carcinoma. The site of involvement in 30 cases were rectum and in 71 cases were colon. The most common symptom was abdominal pain, constipation and rectal bleeding. The time interval between onset of symptom to diagnosis of disease in 58 cases was >6 mth. Family history of cancer in 36 cases was positive. Right colon cancer in young patient was significantly more than older [P<0.05]. Positive family history of cancer in right colon cancer was significantly more other than. Positive family history of cancer in young patient was more than other [P<0.05]
Conclusion: according to this study, colorectal cancer was high. Therefore, it is necessary to pay more attention to the symptom of young patient and providing a screening program in patients over 50 years old and young patients with positive family history