[Origin of left coronary artery arising from the right coronary cusp]

Anomalous coronary artery origin is a rare clinical entity with varied clinical outcomes ranging from asymptomatic to sudden cardiac death. The incidence of anomalous origin of left coronary artery arising from the right coronary cusp is 0.3-1%. CT angiography is the choice method for coronary anomalies, but often coronary angiography in RAO [right anterior oblique] view shows the coronary course. We present a case that referred to our hospital with post myocardial infarction angina for coronary angiography. A resting 12-lead electrocardiogram showed ST-segment elevation in leads v2, v3, v4. A transthoracic echocardiogram indicated LVEF 25% [Left ventricular ejection fraction], septal akinesia and apical dyskinesia. Coronary Angiography showed an anomalous origin of the left coronary artery from the right coronary cusp and significant stenosis in LAD [left anterior descending] and LCX [left circumflex] arteries with poor run off

effect of carnitine on serum lipids in hemodialysis patients with heart failure

Background and purpose: Hyperlipidemia is one of the most important cardiovascular risk factors in hemodialysis patients. As adequate amount of carnation is essential for fatty acids metabolism and prevention of hyperlipidemia, This research was conducted to study the effect of carnitine on serum lipids in hemodialysis patients

Methods and Materials: 20 patients with at least 3 months hemodialysis duration participated in this double-blind clinical trial. Randomly and equally, they were divided into two [case and control] groups. Cases received 1g carnitine and controls received placebo daily. Cholesterol and Triglyceride levels were measured prior to the study as well as 3 and 6 months after administration. SPSS package and ANOVA, t-test and chi-squre tests were used far analysis

Results: There were not significant difference in mean of cholesterol and triglyceride levels in two groups as well as in repeated measurements. Also, no significaut changes were observed in each group 3 and 6 months after administration

Conclusion: Carnitine did not have any effect on serum lipids in hemodialysis patients