Malignant transformation of multiple dermal cylindromas

Cylindromas are benign tumors appearing as small solitary slow growing nodules on the head and neck. Multiple cylindromas may form a turban tumor. Here, we report an unusual case of multiple cylindroma with transformation to cylindrocarcinoma. The patient is a 61-year-old woman who developed a cylindrocarcinoma on a pre-existing cylindroma of head and neck, with deformity of head due to soft tissue masses, lytic lesions of scalp with invasion to brain, and destruction of orbit leading to unilateral visual loss

Post surgical desmoid tumors in familial adenomatous polyposis: a case report

Literature review indicates that desmoid tumors are exceedingly common in familial adenomatous polyposis [FAP], where the comparative risk is 852 times that of the general population. Prior abdominal surgery has been found in as many as 68% of FAP patients with abdominal desmoid. Fifty-five percent develop these lesions within 5 years of surgery. We describe a 45-year-old patient with Gardner's syndrome complicated by a desmoid tumor 2 years after he had a prophylactic colectomy

Tuberculous meningoencephalitis: intracranial tumoral presentation

A 37-year-old Iranian woman presented acutely with decreased level of consciousness and bi-lateral mydriasis to the emergency ward. CT scan and MRI showed a large intracranial mass in the left frontotemporoparietal region of the cerebrum. The clinical and imaging findings were suggestive of an intracranial tumor. Frontotemporal lobectomy was performed and the resected specimen contained white caseating material. Grossly, the resected specimen was white and firm. Microscopically multiple granulomatous le-sions with epitheliod histiocytes and Langerhans giant cells and central caseation were seen, surrounded by inflammatory infiltration of plasma cells and neutrophils as well as meningeal congestion. These findings were compatible with necrotizing granulomatous encephalitis of tuberculosis. Parenchymal CNS tuberculosis with or without extra-cerebral manifestations may present as a space-occupying lesion. Because a tuberculoma is rarely suspected especially if there is atypical morphology, biopsy is required to establish the diagnosis and specific treatment