Depression following mania: a retrospective study in Bahrain

In a retrospective study conducted on 40 inpatients admitted to the Psychiatric Hospital, Bahrain, for treatment of hypomania during the years 1986-1990, we observed that depressive symptoms occurred in 40% of cases during the first three months after euthymia. The data analysis included age, sex, past history of mania and depression, family history of psychiatric illness, neuroleptic and lithium therapy. A past history of depression had a significant association with the occurrence of depression following mania