Is the so-called "immune" reaction to smallpox vaccination a misnomer?

1. Vaccine virus, either potent or heated, can produce reactions which may be described as immediate or immune2. The morphologic characteristics of the reactions are the same in both potent and heated vaccines; 3. While those produced by heated vaccine tend to regress beginning the 3rd day and completely disappear by the 6th day after vaccination, those produced by potent vaccine continue to develop to their maximum intensity until about the 10th day; and4. Areolo-vesicular reactions with cloudy fluid inside the vesicles are also produced by heated inactivated virus as early as 24 hours after vaccination. (Conclusion)