ABSTRACT
Considerable research efforts have been made in recent years towards the development of silica mesoporous nanocomposite as drug delivery system. Numerous reports are available in literature for the synthesis of mesoporous nano materials. In present work two distinct mesoporous MCM-41 nanocomposite (MCM-41-A and MCM-41-B) were synthesized and characterized by different instrumental techniques such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy, FTIR and nitrogen adsorption desorption analyses. Both the mesoporous nanocomposite was synthesized with different hydrothermal treatment and effect on mesoporosity was determined. Evaluation data revealed MCM-41-A MSNs with regular spherical shape with high degree of mesoporosity whereas MCM-41-B MSNs were lack of mesoporous characteristics. For instance, hydrothermal treatment significantly affects the physical properties like surface area, pore volume and pore diameter of the MSNs.