ABSTRACT
40 cases postmenopausal women with breast cancer constituted the study group and 20 sex and age matched formed the control group. The study group of untreated patients showed nonsignificant decrease in molybdenum but significant decrease in blood xanthine oxidase and riboflavin levels. Tamoxifen treated patients showed nonsignificant increase in molybdenum, after 3 months, significant increase after 6 months and significant increase in xanthine oxidase and riboflavin levels. Thus tamoxifen when given in breast cancer helps in amelioration of the diseased condition.
Subject(s)
Antineoplastic Agents, Hormonal/therapeutic use , Breast Neoplasms/blood , Female , Humans , Middle Aged , Molybdenum/blood , Postmenopause , Riboflavin/blood , Tamoxifen/therapeutic use , Xanthine Oxidase/bloodABSTRACT
40 cases of breast malignancy constituted the study group and 10 sex matched formed the control grp. Serum level of copper was estimated by atomic absorption photometry and ceruloplasmin was done by Houchin's method. The study group showed significant hypercupremia and increased level of serum ceruloplosmin. It was postulated that levels copper and ceruloplasmin may help in prognosis & diagnosis of disease.