ABSTRACT
Background: preterm labor is a major cause of perinatal morbidity and mortality and it might be predicted by assessing the cervical change
Objective: to assess the association between absences of cervical gland area [CGA] and spontaneous preterm labor [SPTL]
Materials and Methods: this prospective cohort study was performed on 200 singleton pregnant women with a history of SPTL, second-trimester abortion in the previous pregnancy or lower abdominal pain in current pregnancy. Each patient underwent one transvaginal ultrasound examination between 14-28 wk of gestation. Cervical length was measured and CGA was identified and their relationship with SPTL before 35 and 37 wk gestation was evaluated using STATA software version 10
Results: the mean of cervical length was 36.5 mm [SD=8.4], the shortest measurement was 9 mm, and the longest one was 61 mm. Short cervical length [
Conclusion: our study showed that cervical gland area might be an important predictor of SPTL which should be confirmed with further researches
ABSTRACT
Background: Normal amniotic fluid predicts normal placental function, fetal growth and fetal well-being
Objective: To determine adverse pregnancy outcomes in borderline amniotic fluid index [API]
Materials and Methods: Pregnant women [37-40 wks] with diagnosis of borderline API between December 2012 and August 2014 were identified. Antepartum, intrapartum and neonatal data were collected and compared with those of pregnant women with normal API. An API less than 8 and more than 5 cm was defined for borderline API. Pregnancy outcomes included Cesarean section for non-reassuring fetal heart rate, rneconium stained amniotic fluid, 5-min Apgar score <7, low birth weight, umbilical cord blood pH at term and NICU admission
Results: Gestational age at delivery in pregnancies with borderline API was significantly lower than normal API. Cesarean section rate for non-reassuring fetal heart rate in women of borderline API was significantly higher and there was an increased incidence of birth weight less than 10th percentile for gestation age in borderline API group. Incidence of low Apgar score and low umbilical artery pH in pregnancies with borderline API was significantly higher than women with normal API. There were no significant difference in the rate of NICU admission and meconium staining in both groups
Conclusion: There are significant differences for adverse pregnancy outcomes, such as C. lion due to non-reassuring fetal heart rate, birth weight less; than 10[th] pertcentile for gestation age, low 5 min Apgar score and low umbilical artery pH between pregnancies with borderline and normal API
ABSTRACT
To evaluate the value of random urinary protein creatinine ratio in prediction of 24h proteinuria in hypertensive pregnancies. Random urine samples and routine 24h urine collections were collected from hypertensive pregnant women [n=100]. Reliability of random urinary protein-creatinine ratio was assessed by receiver operator characteristic [ROC] curve to detect significant proteinuria [>/=300mg/day] using 24h. Urine protein as a gold standard. Forty six patients [46%] had significant proteinuria. The random protein creatinine ratio was correlated to 24h urine protein excretion [r[2]=0.777, P<0.001] Area under ROC curve to predict proteinuria was 0.926 [95% CI: 0.854-0.995, P<0.001]. A cut off value of 0.22mg/mg for protein creatinine ratio best predicted significant proteinuria with sensitivity, specificity, positive and negative predictive values of 87%, 92.6%, 90.6% and 89.3% respectively. Random urinary protein creatinine ratio is a simple inexpensive and excellent alternative to 24h urine collection. It's helpful in diagnosis of preeclampsia and can be used as a pre admission test in PIH cases