Correlations between Microcomputed Tomography and Bone Histomorphometry in Korean Young Females

The bone mass and microarchitecture are important determinants of bone strength, with microarchitectural deterioration being one of the specific changes associated with osteoporosis. The purpose of this study was to evaluate and compare the results of microcomputed tomography (micro-CT) and histomorphometry of biopsied specimens. A bone biopsy was performed on the iliac crest of 10 normal premenopausal Korean women. Measurements of the bone mineral density (BMD), micro-CT, and bone histomorphometry were performed. The bone volume, as determined by both micro-CT and histomorphometry, was significantly correlated (r=0.88, p < 0.01). The osteoid surface was correlated with both the bone volume (r=0.84, p < 0.01) and the structure model index (SMI) (r= -0.89, p < 0.01) measured by micro-CT. The SMI was correlated with both the bone volume (r=-0.85, p < 0.01) and the total hip BMD (r=-0.65, p < 0.05). In conclusion, some, but not all of the parameters of the micro-CT, were well correlated with the bone histomorphometric results. Micro-CT and histomorphometry appear to be complementary techniques in the study of bone microarchitecture.

Aging and Gender Specific Quality of Life: Seventh crucial life

The role of doctors in ancient China was that of Prevention as opposed to curios, and illness was a just cause for execution. Much later, at the time of the French Revolution. Saint-Just evolved a new concept around the idea of happiness. As we can see in modem times, this idea is no longer a fad but a precious right that we humans can cherish and also means the quality and longevity of life. Of course this meaning cannot be the same for all people, and more so as humans are the most complex of all living nature. Even all this stage I feel it is so difficult to discuss the quality of life per so, as we all have different physical, emotional and material needs and modem science still cannot uncover the mystery of life. 4 concept of quality of life already been included in the WHO definition of has health where well-feeling is as necessary as well-being, both being of concern to medical doctors. I personally feel that the role of doctors is not simply to cure diseases but how we can help patients extend their span of life to live more actively and fulfillingly, the quality of life should not only deal with the prevention and cure of illnesses, but touch all aspects of aging. Aging in itself is quite mutual with any kind of disease and disability; the expansion and reduction of our lifespan depends so much on the exposure to disease and how aging affects both sexes diversely is one important factor when considering the quality of life. It could be said that our bodies are always in a state of homeostasis where biological destruction and development arise. This process is naturally called aging. However, passing through every seven year cycle we are dressing up our quality of life against various physical and mental experiences, while maintaining a steady state of homeostasis, and therefor face aging and different environmental changes. As a physician and being in a profession where we can influence ones quality of life. I feel it is imperative to study how aging is related to endocrinology and its disease, and the different outcomes of diseases and symptoms shown by males and females. In my study, I have generally classified our life span into seven crucial stages of aging and dealt with "Aging and gender how its physiology affects the quality of life".