ABSTRACT
Antioxidants may have a positive effect on human health since they can protect the human body against deterioration by reactive oxygen species (ROS). Chitosan has many promising properties as nontoxic, biocompatible, biodegradable, antimicrobial and recently antioxidant properties. Most of the reports on the antioxidant activity of chitosan are based on the ability of amine and hydroxyl group to scavenge free radical to form stable macromolecular radical. In the current study, a new chitosan derivative with extra free amine groups was evaluated using two popular antioxidant evaluation methods (uninhibited/inhibited hyaluronan degradation and decolorization of ABTS method). The result obtained in our study show increase the activity of aminated chitosan for scavenging free radicals than chitosan itself.
ABSTRACT
In this study, new cinnamyl chitosan schiff base was evaluated as antioxidant material. Antioxidant activity was measured by two different popular methods (uninhibited/inhibited hyaluronan degradation and decolorization of ABTS methods). the results show decrease the hydrogen donation behavior of chitosan after coupling with cinnamaldehyde, in the other hand, ABTS method show increase the electron donation activity of cinnamyl chitosan than the chitosan itself.