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Rev. méd. Chile ; 123(10): 1235-42, oct. 1995. tab
Article in Spanish | LILACS | ID: lil-164897

ABSTRACT

Sprague-Dawley rats are frequently used in experiments and their normal hematological, serological and anatomical parameters are not easily available. The aim of this study was to measure these parameters in adult Sprague-Dawley rats. 24 rats (12 males) whose weight ranged between 200 and 300 g raised at the Instituto de salud Pública in controlled environment conditions and fed with pellets were studied. After a 24 h fast animals were anesthetized with Droperidol and Ketamine and after obtaining a cardiac blood for glucose, calcium, amylase, total proteins, cholesterol, AST, ALT, bilirrubin, alkaline phosphatases, electrolytes and complete blood count were determined. Heart, lung, pancreas, kidney and testicle mean weight was also calculated. Male and female rats had significant differences in packed red cell volume, white blood cell count and hemoglobin


Subject(s)
Rats , Animals , Hemoglobinometry/statistics & numerical data , Leukocyte Count , Blood Chemical Analysis , Hematocrit/statistics & numerical data , Organ Size , Reference Values , Rats, Sprague-Dawley/anatomy & histology , Rats, Sprague-Dawley/blood
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