ABSTRACT
Chorioangioma is the most frequent placenta non trophoblastic tumor. It is a benign arteriovenous malformation, that can be unique, multiple or more rarely diffuse within the placenta. They can be diagnosed by ecography and they are observed as subchorionic compound injuries of hipoecogenic images around an ecogenic center. A case diagnosed during week 28 of pregnancy will be reviewed which was referred from primary care to the High Risk Fetus Unit with ecographic findings of placentary tumor. Its handling is described and later pathological diagnose compatible with placenta tumor: chorioangioma.
El corioangioma o hemangioma de la placenta es el tumor no trofoblástico más frecuente de la placenta. Es una malformación arterio-venosa benigna, que puede ser única, múltiple o más raramente difusa dentro de la placenta. Deben ser diagnosticados por ultrasonografía y se observan como lesiones subcoriónicas compuestas de imágenes hipoecoicas alrededor de un centro ecogénico. Se revisa un caso diagnosticado durante semana 28 de embarazo la cual fue referida desde su consultorio a la unidad de Feto de Alto Riesgo por hallazgo ultrasonográfico de masa placentaria. Se describe su manejo y posterior diagnóstico patológico de tumor placentario compatible con corioangioma.
Subject(s)
Humans , Female , Pregnancy , Adult , Placenta Diseases , Hemangioma , Pregnancy Complications, Neoplastic , Placenta/pathologyABSTRACT
Hepatitis C virus (HCV) infection is very common among hemodialysis (HD) patients. Transmission of Infection in this setting has been related to the number of blood transfusions, the duration of hemodialysis and to nosocomial transmission of virus in the dialysis unit. We conducted a study of 74 HD patients to determine the frequency of HCV at a single point in time (cross-sectional analysis), and to evaluate the association between HCV infection and patients' demographic, clinical and biochemical features. Serum samples were tested for anti-HCV antibodies using a third-generation enzyme-linked immunosorbent assay (ELISA). In the case of a positive result, third-generation recombinant immunoblot and HCV RNA detection by polymerase chain reaction (PCR) tests were performed. Collected data included the patient's age, gender, time on HD, number of blood transfusions and serum alanine aminotransferase (ALT) activity. Twenty-nine patients (29/74.4 percent) were found to be HCV positive using a third generation ELISA assay. From these 29 patients, 27 were also positive by recombinant immunoblot assay and 2 patients had indederminate results. In the subgroup of anti-HCV ELISA positive, 20 (69 percent) of the 29 patients had detectable HCV RNA. The HCV RNA positive patients had received more blood transfusions (15ñ3 vs.5ñ1 units of packed red blood cells, p<0.0001) and had been on HD for a longer period of time than the HCV RNA negative patients (65ñ32 vs.32ñ29 months, p<0.0001). Mean serum ALT levels were significantly higher in the HCV RNA positive group (30ñ18 vs.15ñ9,p<0.0001). We were unable to determine the most likely mode of transmission in our unit, but these results emphasize the need for strict adherence to blood collecting and handing precautions, careful attention to hygiene in the dialysis units, and sterilization of dialysis machines in order to properly combat this frequent infection.