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1.
São Paulo med. j ; 141(3): e20211028, 2023. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1432437

ABSTRACT

ABSTRACT BACKGROUND: Residents play the role of teachers in almost one-quarter of their activities in residency programs. OBJECTIVE: To evaluate whether a 45-minute class using summarize, narrow, analyze, probe, plan, and select (SNAPPS) could improve psychiatry residents' case discussion skills in diverse practical learning settings. DESIGN AND SETTING: This case-control, randomized, blinded study was conducted in a psychiatry hospital at Fortaleza-Ceará. METHODS: Using "resident as teacher" (RaT), objective structured teaching encounters (OSTEs), and SNAPPS, we conducted a study with 26 psychiatry residents. We analyzed video footage of psychiatric cases in three settings: outpatient, nursing, and emergency. An intervention was held two months later with the residents, who were then assigned to two groups: group A (lecture on SNAPPS) and group B (lecture on a topics in psychiatry). Shortly after the lectures, they were video recorded while discussing the same cases. Three blinded examiners analyzed the videos using an instrument based on the Stanford Faculty Development Program (SFDP-26). RESULTS: We found high internal consistency among external examiners and an interaction effect, group effect, and moment effect (P < 0.05). The residents who received the SNAPPS lecture scored significantly higher than their counterparts who received a traditional case presentation. CONCLUSION: This study indicates the efficacy of SNAPPS over traditional case presentation in all three settings as assessed by OSTEs and supports its implementation to improve the teaching of clinical reasoning.

2.
Arch. endocrinol. metab. (Online) ; 65(5): 570-578, 2021. tab, graf
Article in English | LILACS | ID: biblio-1345201

ABSTRACT

ABSTRACT Objectives: The purpose of this study was to investigate the heterogeneity of the association between glycemic variability and oxidative stress markers in T1DM patients under daily life insulin treatment. Subjects and methods: We studied, in a cross-sectional analysis, 76 T1DM patients without clinical chronic diabetes complications and 22 healthy individuals. Were evaluated the short-term glycemic variability (STGV), long-term glycemic variability (LTGV), oxidative stress markers [8-isoprostaglandin-F2α (Ur-8-iso-PGF2α), nitric oxide (NO), thiobarbituric acid reactive substances (TBARS) and erythrocytes reduced/oxidized glutathione (GSH/GSSG)] and biochemical dosages (glycaemia, HbA1c, lipidogram, albuminuria). Results: Plasmatic NO was positively associated with LTGV (last year average of HbA1c) (8.7 ± 1.6% or 71 ± 18 mmol) (rS: 0.278; p: 0.042). Plasmatic TBARS, erythrocytes GSH/GSSH and Ur-8-iso-PGF-2α didn't show correlation with glycemic variability. GSH/GSSG was inversely correlated with LDL-cholesterol (rS: - 0.417; p: 0.047) and triglycerides (rS: −0.521; p: 0.013). Albuminuria was positive correlated with age (rS: 0.340; p: 0.002), plasmatic NO (rS: 0.267; p 0.049) and TBARS (rS: 0.327; p: 0.015). Conclusion: In daily life insulin treatment, young T1DM patients have higher plasmatic NO than healthy subjects. However, the correlation between glycemic variability and oxidative stress markers is heterogeneous. Lipid profile and albuminuria are associated with different oxidative stress markers. These data collaborate to explain the controversial results in this issue.


Subject(s)
Humans , Diabetes Mellitus, Type 1/drug therapy , Insulins/therapeutic use , Blood Glucose , Glycated Hemoglobin/analysis , Cross-Sectional Studies , Oxidative Stress
3.
Arq. bras. endocrinol. metab ; 55(8): 638-645, nov. 2011. tab
Article in English | LILACS | ID: lil-610467

ABSTRACT

OBJECTIVE: The aim of this study was to establish the best cutoff values for waist circumference (WC), body mass index (BMI) and HOMA-IR (HR) to identify a cluster (> 3) of cardiovascular risk factors (CVRF) in normal glucose-tolerant (NGT) Brazilian children and adolescents. SUBJECTS AND METHODS: Cross-sectional study of 319 individuals (aged 10 to 19y) from a southern Brazilian city. Gender-specific receiver-operating characteristics (ROC) curves were constructed to assess cutoffs values of BMI (kg/m², WC (cm), and HR. RESULTS: The areas under the ROC curves to detect a cluster of CVRF were 0.92, 0.93 and 0.68 (females), and 0.93, 0.93 and 0.89 (males), for WC, BMI and HR, respectively. The cutoff values were 83.0 and 80.5 cm (WC), 22.7 and 20.4 kg/m2 (BMI), and 1.65 and 1.95 (HR), for females and males, respectively, to detect the cluster of CVRF. CONCLUSION: These values of BMI, WC-) and (HR) detected a high proportion of NGTt Brazilian children and adolescents with a cluster of CVRF.


OBJETIVO: O objetivo deste estudo foi estabelecer os melhores valores de corte para circunferência abdominal (CA), índice de massa corpórea (IMC) e HOMA-IR (HR) para identificação da concomitância de um conjunto de fatores de risco cardiovascular (> 3) em crianças e adolescentes brasileiros com tolerância normal à glicose (TNG). SUJEITOS E MÉTODOS: Estudo transversal realizado em uma cidade do sudeste do Brasil com 319 indivíduos de 10 a 19 anos de idade. Curva ROC para cada gênero foi utilizada para estabelecimento dos valores de IMC (kg/m²), CA (cm) e HRR. RESULTADOS: As áreas sob as curvas ROC para detectar o conjunto de fatores cardiovascular foram 0,92, 0,93 e 0,68 (meninas) e 0,93, 0,93 e 0,89 (meninos) para CA, IMC e HR, respectivamente. Os valores de corte foram 83,0 e 80,5 cm (CA), 22,7 e 20,4 kg/m² (IMC) e 1,65 e 1,95 (HR), para meninas e meninos, respectivamente, para detecção do grupo de fatores de risco cardiovascular. CONCLUSÃO: Esses valores de IMC,CA e HR detectaram uma porcentagem significativa de crianças e adolescentes brasileiros com TNG e elevado risco cardiovascular.


Subject(s)
Adolescent , Child , Female , Humans , Male , Young Adult , Body Mass Index , Blood Glucose/analysis , Cardiovascular Diseases/diagnosis , Insulin Resistance/physiology , Waist Circumference/physiology , Brazil/epidemiology , Cardiovascular Diseases/epidemiology , Epidemiologic Methods , Glucose Tolerance Test , Reference Values , Sex Distribution
4.
RBM rev. bras. med ; 66(1/2)jan.-fev. 2009.
Article in Portuguese | LILACS | ID: lil-540105

ABSTRACT

A crescente prevalência de diabetes mellitus nos últimos anos no mundo desenvolvido e em desenvolvimento fez com que essa doença ganhasse uma importância sem precedentes. Levando-se em conta o grande impacto das complicações diabéticas na mortalidade e morbidade e a contribuição do diabetes como fator de risco cardiovascular, o diagnóstico precoce e a introdução rápida do tratamento são mandatórios para manutenção da qualidade de vida. Recentemente novas abordagens comportamentais e farmacológicas têm sido desenvolvidas, melhorando e facilitando a terapêutica do paciente diabético.


Subject(s)
Humans , Male , Female , Diabetes Mellitus/classification , Diabetes Mellitus/diagnosis , Diabetes Mellitus/therapy , Insulin/classification , Prediabetic State/prevention & control
5.
RBM rev. bras. med ; 58(11): 806-: 810-: 812-: passim-808, 810, 812, nov. 2001. tab
Article in Portuguese | LILACS, SES-SP | ID: lil-319653

ABSTRACT

A doença de Graves é a causa mais comum de hipertireoidismo. É uma doença auto-imune caracterizada pela presença de anticorpos contra o receptor de TSH, também chamados de imunoglobulinas estimuladoras da tiróide. Como o tratamento do hipertireoidismo defere, de acordo com a etiologia, o diagnósico correto é imprescindível antes da terapia ser instiuída.(au)


Subject(s)
Humans , Hyperthyroidism , Graves Disease
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