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An. Fac. Med. (Perú) ; 80(4): 465-469, oct.-dic 2019. ilus, tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1142059

ABSTRACT

Introducción. El poblador normal de altura tiene un metabolismo intermediario diferente al del poblador de nivel del mar, caracterizado por una menor glicemia. En pacientes con diabetes tipo 2, que residen en grandes altitudes, el efecto que tiene el ejercicio aún no ha sido completamente estudiado. Objetivos. Estudiar el efecto del ejercicio, de corta duración y casual, sobre el control metabólico basal y post-prandial en personas con diabetes tipo 2 (DM2), residentes a 3395 msnm. Métodos. A 14 mujeres y 11 varones con DM2, residentes de altura (Cusco, 3395 msnm), de 40 a 72 años, se les efectuó dos pruebas: basal (A) y post ejercicio pre-prandial (B) consistente en una caminata, durante 30 minutos, a 4 km/hora (3 METS). En ayunas y luego de un desayuno con 730 Kcal (55,4% de grasas, 37,2% de carbohidratos y 7,3% de proteínas), se midió en sangre glucosa, colesterol total, HDL, triglicéridos, insulina y ácidos grasos no esterificados (AGNE) durante seis horas. Adicionalmente, se midieron niveles de colesterol VLDL, LDL, NoHDL y HOMA-IR. Resultados. Se encontró disminución estadísticamente significativa (p<0,01) entre los promedios de glicemia basal (230,2 mg/dL) y post-prandial (115 mg/dL). Conclusión. El ejercicio mejoró el control glicémico post prandial en DM2 en la altura.


Introduction. The population living on high altitudes areas has a different intermediate metabolism than people who is living on coastal areas, characterized by lower glycemia levels. In patients with type 2 diabetes, who reside at high altitudes, the effect of exercise has not yet been fully studied. Objective. To study the effect of short duration and casual exercise, on basal and post-prandial metabolic control in people with type 2 diabetes (DM2), residents at 3395 msnm. Methods. 14 women and 11 men with DM2, residents at high altitudes (Cusco, 3395 msnm), between 40 to 72 years old, who were intervened with two tests: baseline (A) and pre-postprandial exercise (B) consisting of a walk, for 30 minutes, at 4 Km/h (3 METS). Glucose, total cholesterol, HDL, triglycerides, insulin and non-esterified fatty acids (AGNE) were measured in the blood on fasting and after a breakfast with 730 Kcal (55,4% fat, 37,2% carbohydrates and 7,3% protein), for six hours. Additionally, total cholesterol, VLDL, LDL, NoHDL and HOMA-IR levels were calculated. Results. Statistically significant decrease (p<0,01) was found between the mean baseline (230,2 mg / dL) and post-prandial (115 mg / dL) glycemia. Conclusion. The exercise improved post-prandial glycemic control in DM2 in people who are living in high altitudes.

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